An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care

We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD³ (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac resuscitation. Experimental results reveal that the IRD³ provides an effective method for rapid delivery without significant drug degradation. Several medical uses and delivery modalities for IRD³ are proposed. Electronic supplementary material  The online version of this article (doi:) contains supplementary material, which is available to authorized users. N. M. Elman and H. L. Ho Duc contributed equally to this work.