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1085例冠状动脉造影患者血清尿酸浓度与冠心病危险因素的相关性
引用本文:张云霞,林梅瑟,林祖近,刘峰,冯湘君.1085例冠状动脉造影患者血清尿酸浓度与冠心病危险因素的相关性[J].中华老年心脑血管病杂志,2005,7(3):160-162.
作者姓名:张云霞  林梅瑟  林祖近  刘峰  冯湘君
作者单位:1. 温州市中医院心内科,浙江,温州,325000
2. 温州心血管医院心内科,浙江,温州,325000
摘    要:目的探讨血清尿酸浓度与冠心病发生的预测价值。方法回顾性分析了1085例因胸痛接受冠状动脉造影的具有至少一个冠心病危险因素的患者,根据冠心病确诊情况分为冠心病组(574例)和非冠心病组(511例),观察血清尿酸浓度与冠心病是否存在相关性。结果冠心病组血清尿酸浓度高于非冠心病组。两组血清尿酸浓度有显著性差异(P<0.01)。多因素逐步回归显示,高尿酸血症是冠心病的独立危险因素。结论高尿酸血症是本组患者预测冠心病的一个独立的危险因素。

关 键 词:冠状动脉疾病  尿酸  冠状血管造影术  危险因素
文章编号:1009-0126(2005)03-0160-03
收稿时间:07 13 2004 12:00AM
修稿时间:2004年7月13日

Relationship between serum uric acid level and risk factors of coronary artery disease in 1 085 cases of coronary angiography
ZHANG Yun-xia,LIN Mei-se,LIN Zu-jin,et al.Relationship between serum uric acid level and risk factors of coronary artery disease in 1 085 cases of coronary angiography[J].Chinese Journal of Geriatric Cardiovascular and Cerebrovascular Diseases,2005,7(3):160-162.
Authors:ZHANG Yun-xia  LIN Mei-se  LIN Zu-jin  
Abstract:Objective To assess the relationship between serum concentration of uric acid and coronary artery disease.Methods 1?085 patients receiving coronary angiography were analyzed for risk factors of coronary artery disease and serum concentration of uric acid was measured.Results There were significant differences in age and incidences of other risk factors between coronary artery disease(CAD) group and non-CAD group. Serum concentration of uric acid in CAD group was much higher than that in non-CAD group(P<0.01). Multivariate logistic regression analysis revealed that hyperuricemia was an independent risk factor of CAD.Conclusion There is a close relationship between serum uric acid and CAD and hyperuricemia may be conducive to the risk stratification.
Keywords:coronary disease  uric acid  coronary angiography  risk factors
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