| chemerin与GDM发病关系的研究 |
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| 引用本文： | 高世芳,孙蕾芳. chemerin与GDM发病关系的研究[J]. 现代妇产科进展, 2012, 21(9): 700-701,705 |
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| 作者姓名： | 高世芳 孙蕾芳 |
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| 作者单位： | 青岛市海慈医疗集团产科,青岛,266003 |
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| 摘 要： | 目的:了解妊娠期糖尿病(GDM)孕妇血清chemerin水平的变化及其临床意义。方法:采用酶联免疫吸附法测定38例GDM患者(GDM组)及40例糖耐量正常孕妇(对照组)血清chemerin水平,同时测定受试者空腹血糖(FPG),三酰甘油(TG),总胆固醇(TC),高密度脂蛋白胆固醇(HDL-C),空腹胰岛素(FINS),计算胰岛素抵抗指数(HOMA-IR)。结果:(1)GDM组血清chemerin水平显著高于对照组(P<0.05)。(2)GDM组FPG、TG、FINS、HOMA-IR水平均显著高于对照组(P均<0.05)。GDM组TC,HDL-C水平与对照组的差异无统计学意义。(3)GDM组血清chemerin水平与TG呈显著正相关(r=0.726,P<0.05)。结论:GDM患者血清chemerin水平升高,可能参与了妊娠期糖尿病孕妇糖代谢紊乱。
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| 关 键 词： | 糖尿病,妊娠 chemerin 胰岛素抵抗 |
The relationship between chemerin and GDM |
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| Gao Shifang,Sun Leifang. The relationship between chemerin and GDM[J]. Current Advances In Obstetrics and Gynecology, 2012, 21(9): 700-701,705 |
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| Authors: | Gao Shifang Sun Leifang |
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| Affiliation: | .Department of Obstetrics,Haici Medical Group,Qingdao 266003 |
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| Abstract: | Objective:To study the relationship between chemerin and GDM.Methods:The serum chemerin levels in pregnant women with GDM(38 cases)and in normal pregnant women(40 cases)were determined individually by Enzyme-linked immunosorbent assay(ELISA).Fasting plasma glucose(FPG),blood glycerin three greases(TG),fasting Insulin levels(FINS),insulin resistance index(HOMA-IR) were also tested.Results:(1) The serum level of chemerin was significantly higher in GDM group than that in control group(P<0.05).(2)The serum levels of FPG,FINS,TG,HOMA-IR were significantly higher in GDM group than that in control group(P<0.05).The serum levels of TG、HDL-C were not significantly different between the two groups.(3)There were significant correlations between the levels of serum chemerin and TG(r=0.726,P<0.05).Conclusions:The levels of serum chemerin in pregnant women with GDM obviously increase,and the levels of serum chemerin may play a role in pregnant women with GDM. |
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| Keywords: | Diabetes,gestational Chemerin Insulin resistance |
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