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| 2型糖尿病患者贫血与微血管病变的相关研究进展 | |
| 引用本文： | 王敏,班博,张梅,汲宝兰,孙冰.2型糖尿病患者贫血与微血管病变的相关研究进展[J].中国全科医学,2020,23(14):1717-1721. |
| 作者姓名： | 王敏 班博 张梅 汲宝兰 孙冰 |
| 作者单位： | 1.272067山东省济宁市，济宁医学院 2.272029山东省济宁市，济宁医学院附属医院内分泌科 *通信作者：孙冰，教授；E-mail：sdsunb@163.com |
| 基金项目： | 山东省自然科学基金资助项目(ZR2016HM65)。 |
| 摘 要： | 贫血在2型糖尿病(T2DM)患者中普遍存在,多项研究表明贫血是糖尿病肾病(DN)、糖尿病视网膜病变(DR)等微血管并发症的危险因素。其可通过诱导缺氧、氧化应激、内皮功能失调等机制参与T2DM患者微血管病变的发生、发展。本文主要探讨贫血与T2DM患者微血管病变的致病关系,研究通过纠正贫血改善T2DM患者微血管并发症预后的可行性。 |
| 关 键 词： | 2型糖尿病 微血管 微血管病变 贫血 综述 |
Recent Developments in Research on Anemia and Microvascular Complications in Patients with Type 2 Diabetes Mellitus |
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| WANG Min,BAN Bo,ZHANG Mei,JI Baolan,SUN Bing.Recent Developments in Research on Anemia and Microvascular Complications in Patients with Type 2 Diabetes Mellitus[J].Chinese General Practice,2020,23(14):1717-1721. | |
| Authors: | WANG Min BAN Bo ZHANG Mei JI Baolan SUN Bing |
| Institution: | 1.Jining Medical University，Jining 272067，China 2.Department of Endocrinology，Affiliated Hospital of Jining Medical University，Jining 272029，China *Corresponding author：SUN Bing，Professor；E-mail：sdsunb@163.com |
| Abstract: | Anemia is a common finding in patients with type 2 diabetes mellitus（T2DM）．Many studies have indicated that anemia is a risk factor for diabetic nephropathy and diabetic retinopathy and other diabetes-related microvascular complications.It may be involved in the development and progression of such complications by inducing hypoxia，oxidative stress，and endothelial dysfunction.The article mainly evaluates the pathogenic relationship between anemia and diabetic microvascular diseases，and studies the feasibility of improving the prognosis of microvascular diseases in T2DM patients by treating anemia. Type 2 diabetes mellitus；Mictovessels；Microvascular complication；Anemia；Review |
| Keywords: | Type 2 diabetes mellitus Mictovessels Microvascular complication Anemia Review |
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