| 重症肌无力的免疫修饰治疗 |
| |
| 引用本文： | 张宁,汤旎,张晓燕,尹榕.重症肌无力的免疫修饰治疗[J].国际免疫学杂志,2020(1):98-102. |
| |
| 作者姓名： | 张宁 汤旎 张晓燕 尹榕 |
| |
| 作者单位： | 甘肃中医药大学临床医学院神经病学;中国人民解放军联勤保障部队第九四○医院神经内科 |
| |
| 基金项目： | 甘肃省自然科学基金(1506RJZA302)。 |
| |
| 摘 要： | 重症肌无力是一种主要由乙酰胆碱受体抗体介导累及神经-肌肉接头的自身免疫疾病.免疫修饰治疗可明显减少重症肌无力患者病死率并提升社会生活质量,但可用免疫抑制剂品种多样且均有剂量相关性的不良反应.目前国内外研究者对符合重症肌无力的免疫抑制剂选取、具体使用方法等问题尚无确切定论,因此有必要对重症肌无力常用免疫修饰治疗的临床应用进行综述,为临床医师在重症肌无力个体化免疫修饰治疗方面提供参考.
|
| 关 键 词： | 重症肌无力 免疫修饰治疗 免疫抑制剂 副作用 |
Immune modification therapy for myasthenia gravis |
| |
| Zhang Ning,Tang Ni,Zhang Xiaoyan,Yin Rong.Immune modification therapy for myasthenia gravis[J].International Journal of Immunology,2020(1):98-102. |
| |
| Authors: | Zhang Ning Tang Ni Zhang Xiaoyan Yin Rong |
| |
| Institution: | (Department of Neurology,Clinical Medical College,Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China;Chinese Peoples Liberation Army Joint Service Support Force 940 Hospital Department of Neurology,Lanzhou 730050,China) |
| |
| Abstract: | Myasthenia gravis is an autoimmune disease that is primarily mediated by acetylcholine receptor antibodies involving the neuromuscular junction.Immunomodification therapy can significantly reduce the mortality and improve the quality of social life of myasthenia gravis patients,but there are many kinds of immunosuppressants and dose-related adverse reactions.And so far,there is no definite conclusion on the selection and the specific use of immunosuppressants.This review summarized the clinical application of immunotherapy in myasthenia gravis,so as to provide a reference for clinicians in the treatment of myasthenia gravis. |
| |
| Keywords: | Myasthenia gravis Immunomodified therapy Immunosuppressive agents Side effects |
| 本文献已被 维普 等数据库收录！ |
|
