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Liver injury in COVID-19: A minireview
Authors:Jian-Nan Zhao  Ying Fan  Shuo-Dong Wu
Affiliation:Jian-Nan Zhao, Ying Fan, Shuo-Dong Wu, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Abstract:In December 2019, an outbreak of unexplained pneumonia was reported in Wuhan, China. The World Health Organization officially named this disease as novel coronavirus disease 2019 (COVID-19). Liver injury was observed in patients with COVID-19, and its severity varied depending on disease severity, geographical area, and patient age. Systemic inflammatory response, immune damage, ischemia-reperfusion injury, viral direct damage, drug induce, mechanical ventilation, and underlying diseases may contribute to liver injury. Although, in most cases, mild liver dysfunction is observed, which is usually temporary and does not require special treatment, the importance of monitoring liver injury should be emphasized for doctors. The risk of COVID-19 infection of liver transplantation recipients caused more and more concerns. In this article, we aimed to review the available literature on liver injury in COVID-19 to highlight the importance of monitoring and treating liver injury in COVID-19.
Keywords:Liver injury   COVID-19   Novel coronavirus   SARS-CoV-2   Hepatoprotective drugs   Pandemic
点击此处可从《World Journal of Clinical Cases》浏览原始摘要信息
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