2010-2014年浙江省肿瘤登记地区子宫体癌发病与死亡分析

目的近年来子宫体癌发病呈现明显上升趋势,为了解浙江省近年来女性子宫体癌流行现状,现分析2010-2014年浙江省肿瘤登记地区子宫体癌的发病与死亡情况。方法数据来源于浙江省肿瘤防治办公室14个登记处(浙江省)上报的子宫体癌发病、死亡和人口资料,分别计算发病(死亡)例数、粗发病率(死亡率)、构成比和顺位、中国标准人口构成(中标率)、Segi’s标准人口构成(世标率)、累积率、截缩率、年龄别发病率(死亡率)、发病率(死亡率)年度变化百分比(annual change percent change,APC)及95%CI等指标。结果2010-2014年浙江省14个肿瘤登记地区共报告子宫体癌新发病例2767例,占女性癌症新发病例的3.08%。子宫体癌发病率为9.46/10万,中标率为6.11/10万,位居女性癌症发病顺位的第8位。子宫体癌发病率呈波动增长趋势,从2010年的9.31/10万上升至2014年的10.28/10万,APC为1.89%(95%CI:-2.90~6.91)。2010-2014年共报告子宫体癌死亡病例797例,占女性癌症死亡病例的2.10%。子宫体癌死亡率为2.72/10万,中标率为1.58/10万,位居女性癌症死因顺位的第13位。子宫体癌死亡率呈现波动下降趋势,由2010年的2.76/10万降至2014年的2.52/10万,APC为-4.28%(95%CI:-13.82~6.33)。结论浙江省子宫体癌发病率呈波动上升趋势,但死亡率呈波动下降趋势,应通过提高早诊早治比例、提高女性自我防护意识和倡导健康生活方式等综合措施做好子宫体癌防控。

Incidence and mortality of corpus uteri cancer in Zhejiang cancer registration areas,2010-2014

OBJECTIVE The incidence of uterine body cancer had shown an obvious upward trend in recent years.This study aimed to understand the epidemic situation of female uterine body cancer in Zhejiang province,the incidence and mortality of corpus uteri cancer in Zhejiang cancer registration areas from 2010 to 2014 were investigated.METHODS Data of corpus uteri cancer incidence and mortality as well as population from 14 cancer registration areas of Zhejiang province were collected.Number of cases,crude rates,proportions,age standardized rates,cumulate rates,cut rates,age-specific rates and annual percentage change(APC,95%CI)of corpus uteri cancer incidence and mortality were analyzed.RESULTS There were 2767 new diagnosed corpus uteri cancer cases in Zhejiang cancer registration areas,accouting for 3.08%of all new cancer cases.The incidence of corpus uteri cancer was 9.46/10^5,and the standardized incidence rate by Chinese population was 6.11/10^5,ranking the 8 th in cancer incidence.The incidence of corpus uteri cancer generally grew from 9.31/10^5 in 2010 to 10.28/10^5 in 2014 with a little fluctuation,and the APC was 1.89%(95%CI:-2.90-6.91).Meanwhile,797 corpus uteri cancer death cases were reported from 2010 to 2014,accouting for 2.10%of all cancer death cases.The mortality of corpus uteri cancer was 2.72/10^5,and the standardized mortality rate by Chinese population was 1.58/10^5,ranking the 13 th in cancer mortality.The mortality of corpus uteri cancer was slowly decreased from 2.76/10^5 in 2010 to 2.52/10^5 in 2014 with a little fluctuation,and the APC was-4.28%(95%CI:-13.82-6.33).CONCLUSIONS Incidence rate of corpus uteri cancer was increased and mortality rate decresead with a little fluctuation in Zhejiang province.Comprohensive mearsures such as improving the proportion of early diagnosis and treatment,enhancing women’s self-protection consciousness and advocating healthy lifestyle and so on should be taken to prevent and control corpus uteri cancer.