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非酒精性脂肪性肝炎诊断研究进展
引用本文:龙健灵, 徐蕙, 曾梦, 杨磊, 郑松柏. 非酒精性脂肪性肝炎诊断研究进展[J]. 药学进展, 2020, 44(3): 201-207.
作者姓名:龙健灵  徐蕙  曾梦  杨磊  郑松柏
作者单位:广州华银医学研究所有限公司;南方医科大学基础医学院病理学系
摘    要:非酒精性脂肪性肝病是一种慢性非传染性疾病。近年来其患病率和发病率不断增高,发病年龄也出现低年龄化趋势,该疾病已取代慢性乙型肝炎成为第一大慢性肝脏疾病。重点综述非酒精性脂肪性肝病中的非酒精性脂肪性肝炎的诊断研究进展,介绍非酒精性脂肪性肝炎的临床病史、病理学诊断、非侵入方法诊断,为临床诊断提供参考。

关 键 词:非酒精性脂肪性肝病  非酒精性脂肪性肝炎  病理诊断  影像学诊断  临床诊断  生物标志物

Research Progress in Diagnosis of Non-alcoholic Steatohepatitis
LONG Jianling, XU Hui, ZENG Meng, YANG Lei, ZHENG Songbai. Research Progress in Diagnosis of Non-alcoholic Steatohepatitis[J]. Progress in Pharmaceutical Sciences, 2020, 44(3): 201-207.
Authors:LONG Jianling  XU Hui  ZENG Meng  YANG Lei  ZHENG Songbai
Affiliation:(Guangzhou Huayin Medical Institute,Guangzhou 510700,China;Department of Pathology,School of Basic Medicine,Southern Medical University,Guangzhou 510515,China)
Abstract:Non-alcoholic fatty liver disease(NAFLD)is a chronic,non-communicable disease.In recent years,the prevalence and incidence of NAFLD have been increasing,while the age of onset has been decreasing.It has replaced chronic hepatitis B as the first chronic liver disease.This article reviews the research progress in the diagnosis of non-alcoholic steatohepatitis(NASH),and introduces the clinical history,pathological diagnosis and non-invasive diagnosis of NASH,in order to provide reference for clinical diagnosis of the disease.
Keywords:non-alcoholic fatty liver disease  non-alcoholic steatohepatitis  pathological diagnosis  imaging diagnosis  clinical diagnosis  biomarker
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