腹腔镜前列腺癌根治术不同入路的临床效果及对患者性功能的影响

目的探讨腹腔镜前列腺癌根治术不同入路的治疗效果及对患者性功能的影响。方法 60例行腹腔镜前列腺癌根治术治疗的患者,根据入路方式的不同分为观察组与对照组,各30例。对照组选择经腹腔入路腹腔镜前列腺癌根治术治疗,观察组选择经后腹膜入路腹腔镜前列腺癌根治术治疗。比较两组患者手术相关指标及手术前后国际勃起功能评分表(IIEF-5)评分。结果观察组手术时间(120.39±8.51)min、胃肠功能恢复时间(1.75±1.08)d、引流时间(3.24±1.37)d、尿管拔除时间(12.01±3.14)d、住院时间(14.36±3.25)d均短于对照组的(185.07±12.44)min、(3.56±1.42)d、(5.43±1.89)d、(16.95±3.47)d、(21.68±5.73)d,术中出血量(422.05±31.86)ml少于对照组的(618.37±50.69)ml,差异均有统计学意义(P<0.05)。术后6个月,两组的IIEF-5评分均较术前提高,且观察组高于对照组,差异均有统计学意义(P<0.05)。结论腹腔镜前列腺癌根治术在前列腺癌患者治疗中可发挥显著应用价值,且经后腹膜入路较经腹腔入路具有微创、术后恢复快等优势,更利于促进其性功能的改善。

Clinical effect of laparoscopic radical prostatectomy with different approaches and its influence on sexual function

Objective To discuss the therapeutic effect of laparoscopic radical prostatectomy with different approaches and its influence on sexual function. Methods A total of 60 patients undergoing laparoscopic radical prostatectomy were divided into observation group and control group by different approaches, with 30 cases in each group. The control group received laparoscopic radical prostatectomy by intraperitoneal approach, and the observation group received laparoscopic radical prostatectomy by retroperitoneal approach. The surgery-related indicators and 5-item version of the international index of erectile function(IIEF-5) score before and after operation were compared between the two groups. Results The operation time(120.39±8.51) min, recovery time of gastrointestinal function(1.75±1.08) d, drainage time(3.24±1.37) d, removal time of drainage tube(12.01±3.14) d and hospitalization time(14.36±3.25) d of the observation group were shorter than those of the control group(185.07±12.44) min,(3.56±1.42) d,(5.43±1.89) d,(16.95±3.47) d and(21.68±5.73) d, and amount of intraoperative hemorrhage(422.05±31.86) ml was less than(618.37±50.69) ml in the control group. The difference was statistically significant(P<0.05). 6 months after operation, IIEF-5 score of both groups were improved than those before treatment, and the observation group was higher than the control group. The difference was statistically significant(P<0.05). Conclusion Laparoscopic radical prostatectomy can play a significant role in the treatment of patients with prostate cancer, and the retroperitoneal approach has the advantages of minimally invasive and quick recovery, which is more conducive to the improvement of sexual function.