| Abstract: | Anoxia and inhibitors of energy metabolism have been studied for their effect on intracellular K and Na concentrations, membrane potential, conductivity, passive and active ouabain-sensitive transport of potassium (86Rb) in neurons of freshwater snail Planorbarius corneus. The X-ray microanalysis has shown that anoxia caused no changes in K and Na concentrations in neurons. NaCN inhibited oxygen uptake by ganglia, but has actually no effect on the membrane potential, conductivity and 86Rb uptake in neurons. Much stronger inhibition of the 86Rb uptake was observed in the presence of 2-deoxy-D-glucose. When both glycolytic and respiratory inhibitors were added, the effect was maximal. It is supposed that glycolysis is the main source of energy to maintain the ion homeostasis in the mollusc neurons. |
