酒石酸布托啡诺与芬太尼用于妇科腹腔镜术后镇痛的比较

目的:评价新型镇痛药酒石酸布托啡诺用于妇科腹腔镜术后镇痛的临床疗效、安全性及不良反应.方法:60 例接受妇科腹腔镜手术的患者随机分成2组,每组30 例,酒石酸布托啡诺组1 mg 静脉推注,芬太尼组50 μg 静脉推注.观察静脉给药前及给药后5,10,15,30 min 时镇痛,镇静评分,心率,收缩压,呼吸频率.术后1,...

Comparative Study on Butorphanol and Fentanyl in Patients Undergoing Gynecological Laparoscopic Operation

Objective ：To evaluate the post - operative analgesic efficacy, security and side - effects of butorphanol compared to fentanyl. Methods：60 patients undergoing gynecological laparoscopic operation were recruited and divided into 2 groups： butorphanol group（30 patients）,fentanyl group （ 30 patients）. The index：the scores of sedation and pain intensity, HR, SBP, FF, were observed at the time of 5 rain, lOmin, 15 min and 30 min before and after the treatment. Post - operative pain intensity was assessed at the time of lh,2h,3h and 4h,by recording visual analogue score（VAS） ,the people who used meperidine and the adverse effects were recorded. Results：The scores of pain were lower and the scores of sedation were higher compared to premedical in butorphanol group and in fentanyl group （P 〈 0. 05 ）. The scores of sedation was higher in butorphanol group than in fentanyl group （P 〈 0. 05 ） The demands of meperidine and the adverse effects showed no significant different in both butorphanol and fentanyl groups（ P 〉 0. 05）. Conclusion ：These doses of bu- torphanol could effectively reduce pain intensity after gynecologi- cal laparescopic operation, the adverse effects were low. When compared to fentanyl, the degree of sedation was higher and the time of relieve pain was longer.