肾复康胶囊中芦丁含量测定 |
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引用本文: | 高颖,辛全涛. 肾复康胶囊中芦丁含量测定[J]. 黑龙江医药, 2011, 24(2): 184-185 |
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作者姓名: | 高颖 辛全涛 |
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作者单位: | 1. 哈尔滨世亨生物工程药业有限公司,哈尔滨 2. 哈药集团三精制药四厂股份有限公司,哈尔滨 |
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摘 要: | 目的:建立高效液相色谱法测定肾复康胶囊中的芦丁含量。方法:色谱柱:用十八烷基硅烷键合硅胶为填充剂(250mm×4.6mm,5μm,岛津);流动相:乙腈-水-磷酸(19:81:0.05);流速1.0ml/min;检测波长:359 nm。理论板数按二苯乙烯苷峰计算应不低于2000。结果:二苯乙烯苷线性范围为0.076~0.285μg(r=0.9996),平均回收率99.4%,RSD 1.1%。结论:该方法为肾复康胶囊的质量控制提供了依据。
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关 键 词: | 肾复康胶囊 芦丁 含量测定 高效液相色谱法 |
Determination of Rutin Content in Shenfukang Capsules by HPLC |
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Affiliation: | Gao Ying,et al Harbin Shiheng Bioengineering Co.,Ltd(Harbin) |
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Abstract: | Objective:To establish high- performance liquid chromatography(HPLC) to the content of rutin in Shenfukang Capsules. Methods: Chromatographic column :with 18 alkyl silane bonding silica gel for filling agent ( 250mm × 4. 6 mm, 5 muon m ,island tianjin) ;Mobile phase:acctonitrile - water 3 -phosphate( gets one- nil 05 ) ;Velocity 1.0 ml/min, Detected wavelength: 359 nm. Theoretical tower number press two styrene glucosidc peak calculation should not below 2000. Results: two styrene glucoside linear range for 0. 076 - 0. 285 μg( r = 0. 9996 ), and the average recovery 99.4%, RSD 1.1%. Conclusion: this method for provides the basis for shenfukang Capsule quality control. |
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Keywords: | Shenfukang Capsules rutin content determination HPLC |
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