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Antifungal de-escalation was not associated with adverse outcome in critically ill patients treated for invasive candidiasis: post hoc analyses of the AmarCAND2 study data
Authors:Sébastien Bailly  Olivier Leroy  Philippe Montravers  Jean-Michel Constantin  Hervé Dupont  Didier Guillemot  Olivier Lortholary  Jean-Paul Mira  Pierre-François Perrigault  Jean-Pierre Gangneux  Elie Azoulay  Jean-François Timsit
Affiliation:1. Inserm UMR 1137-IAME Team 5-DeSCID: Decision SCiences in Infectious Diseases, Control and Care INSERM/Paris Diderot, Sorbonne Paris Cité University, Paris, France
2. Grenoble 1 University, U823, Rond-point de la Chantourne, 38700, La Tronche, France
3. Medical ICU, Chatiliez Hospital, Tourcoing, France
4. Paris Diderot Sorbonne Cite University, and Anaesthesiology and Critical Care Medicine, Bichat-Claude Bernard University Hospital, APHP, Paris, France
5. Perioperative Medicine Department, Clermont-Ferrand University Hospital, Clermont-Ferrand, France
6. Surgical ICU, Amiens University Hospital, Amiens, France
7. Inserm UMR 1181 “Biostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases” (B2PHI), 75015, Paris, France
8. University Paris Descartes, Necker Pasteur Center for Infectious Diseases, Necker Enfants-Malades Hospital, IHU Imagine, Paris, France
9. Pasteur Institute, National Reference Center for Invasive Mycoses and Antifungals, CNRS URA3012, Paris, France
10. Medical ICU, Cochin University Hospital, APHP, Paris, France
11. Paris Descartes, Sorbonne Paris Cité University, Paris, France
12. Medical-Surgical ICU, Montpellier University Hospital, Montpellier, France
13. Mycology, Rennes University Hospital, Rennes, France
14. Medical ICU, Saint-Louis University Hospital, Paris, France
15. Medical and Infectious Diseases ICU, Paris Diderot University/Bichat University Hospital, APHP, 46 rue Henri Huchard, Paris, 75018, France
Abstract:
Keywords:
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