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冠脉病变程度和心率变异相关性研究
引用本文:李上共,黄元伟,朱建华,陈君柱,胡申江,张芙荣,赵力. 冠脉病变程度和心率变异相关性研究[J]. 生物医学工程研究, 1996, 0(4)
作者姓名:李上共  黄元伟  朱建华  陈君柱  胡申江  张芙荣  赵力
作者单位:浙江医科大学附属一院心内科
摘    要:本文采用24小时动态心电图方法对冠心病患者和正常对照组进行心率变异时域和频域分析。结果发现单支冠脉病变组SDNN(P<0.05)、TP(P<0.05)和LF(P<0.01)低于对照组,多支冠脉病变组SDNNindex、TP和LF(均P<0.05)低于单支冠脉病变组.提示迷走神经和交感神经波动幅度下降与冠脉病变程度有关,后者是猝死的原因。

关 键 词:心率变异,冠状动脉疾病,植物神经系统,动脉造影

DECREASED MAGNITUDE OF HEART RATE VARIABILITY IN CORONARY ARTERY DISEASE:ITS RELATION TO ANGIOGRAPHIC SEVERITY
Li shanggong, Huang Yuanwei, Zhu Jianhua, Chen Junzhu, Hu Shenjiang, Zhang Fulong, Zhao Li. DECREASED MAGNITUDE OF HEART RATE VARIABILITY IN CORONARY ARTERY DISEASE:ITS RELATION TO ANGIOGRAPHIC SEVERITY[J]. Journal Of Blomedical Englneerlng Research, 1996, 0(4)
Authors:Li shanggong   Huang Yuanwei   Zhu Jianhua   Chen Junzhu   Hu Shenjiang   Zhang Fulong   Zhao Li
Abstract:The time domain and frequency domain of heart rate variability were studied from 24-hour electrocardiography in 23 patients referred for coronary angiography:6 patients had multivessel disease(Group M).17 patients had one-vessel disease(Group S),and 20 healthy control(Group C).The following four frequency domain measures and fivetime domain measures were obtained:VLF,0.0033-0.04Hz,LF,0.04-0.15Hz, HF,0.15-0.40Hz,TP,0-0.50Hz,SDNN SDANN,SDNN index,the square rMSSD,PNN50.Itwas showed that SDNN, TP LF(P< 0.05,P< 0.05,P< 0.01,respectively)were decreasedin Group S compared with Group C. SDNN index,TP and LF(all P<0.05)decreased inGroup M compared with Group S.These results indicate that coronary artery disease is asso-ciated with the impaiwnent of autonomic nervous system function,and that decrease in thefluctuational magnitude of autonomic nervous system(Vagal dominant)tone correlates withthe angiograophic severity.
Keywords:Heart rate variability Coronary artery disease Autonomic nervoussystem Angiography  
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