基质金属蛋白酶-9与炎症反应研究进展 |
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作者姓名: | 高颖 蔡定芳 |
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作者单位: | 1.复旦大学中山医院中医科,上海,200032 |
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摘 要: | MMP - 9 is one of the family of matrix metalloproteinases, which degrades extracellular matrix. MMP- 9 is induced by many inflammatory factors, including IL - 1β, IL - 8 and TNF - α. Mean-while, MMP - 9 potentiates inflammatory factors by aminoterminal processing. The signal transduction by which inflammatory factors induce MMP - 9 is also an important part in recent research. This review will give a sunmamy in all these fields.
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关 键 词: | 基质金属蛋白酶类 炎症 信号转导 |
文章编号: | 1000-4718(2003)08-1133-04 |
收稿时间: | 2002-04-30 |
修稿时间: | 2002-04-30 |
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