阿奇霉素联合盐酸洛美沙星治疗非淋菌性尿道炎的临床研究

目的：探讨临床中阿奇霉素与盐酸洛美沙星联合治疗非淋菌性尿道炎的临床疗效。方法：选取100例非淋菌性尿道炎患者为研究对象，将其按照随机数字法分为研究组和对照组，均50例。对照组给予常规的阿奇霉素治疗，研究组给予阿奇霉素与盐酸洛美沙星联合治疗，观察两组的临床治疗效果。结果：研究组治疗总有效率为94．0％，对照组治疗总有效率为72．0％，研究组治疗总有效率明显的高于对照组（P〈0．05）。研究组复发率为6．0％，对照组复发率为18．0％，研究组复发率明显的低于对照组（P〈0．05），统计学有意义。研究组不良反应发生率为2．0％，对照组不良反应发生率为12．0％，研究组不良反应发生率明显的低于对照组（P〈0．05）。结论：临床中对于非淋菌性尿道炎患者应用阿奇霉素与盐酸洛美沙星联合治疗效果显著，能够有效的提高临床治疗效果，且不良反应少，复发率低，值得临床中应用。

Clinical study of azithromycin combined with lomefloxacin hydrocldoride in the treatment of non - gonococciurethritis

Objectives： To investigate the clinical efficacy of azithromycin combined with lomefloxacin hydrochloride in the treatment of non -gonococci urethritis （NGU）. Methods： 100 NGU patients were selected andrandomly divided into the study group and the control group, each of 50 cases. The control group received conven- tional treatment of azithromycin, while additional lomefloxacin hydrochloride was given to the study group. The clini- cal effect in both groups was observed. Results： The total effective rate of study group and control group was 94.0% and 72.0% respectively, with statistically significant difference （ P 〈 0.05）. The recurrence rate of study group and control group was 6.0% and 18.0% respectively, with statistically significant difference （ P 〈 0.05 ）. The inci- dence of adverse reactions of the study group and control group was 2.0 % and 12.0% respectively, with signifi- cantly difference （ P 〈 0.05）. Conclusion ： Azithromycin combined with lomefloxacin hydrochloride is of significant clinical efficacy for NGU patients, with fewer adverse reactions and low recurrence rate, worthy of clinical applica- tion.