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远志抗衰老作用的研究
引用本文:闫明,李萍. 远志抗衰老作用的研究[J]. 实用药物与临床, 2006, 9(1): 22-23
作者姓名:闫明  李萍
作者单位:辽宁省人民医院药剂科,沈阳,110016;吉林大学,长春,130021
摘    要:目的探讨远志的抗衰老机制。方法采用D-半乳糖致小鼠衰老模型,观察不同剂量的远志提取物对小鼠血清中SOD和肝细胞中GSH-PX活力的影响。结果远志水提物可明显提高小鼠血清中SOD和肝细胞中GSH-PX的活力,降低MDA含量。结论远志提取物可通过清除机体生成的过多自由基、改善机体的抗氧化能力,发挥延缓衰老的作用。

关 键 词:远志  D-半乳糖  抗衰老
文章编号:1673-0070(2006)01-0022-02
收稿时间:2005-08-20
修稿时间:2005-08-20

Studies on antiaging action of Polygala tenuifolia Wild
YAN Ming,LI Ping. Studies on antiaging action of Polygala tenuifolia Wild[J]. Practical Pharmacy and Clinical Remedies, 2006, 9(1): 22-23
Authors:YAN Ming  LI Ping
Abstract:Objective To study the antiaging mechanism of Polygala tenuifolia Wild. Methods The Aging mice induced by Dgalactose were filled with the extracts of Polygala tenuifolia Wild. of different doses for 4 weeks. The activity of serum SOD and hepatocellular GSH-PX of mice were observed. Results The extracts could obviously enhance the activity of SOD in serum and hepatocellular GSH-PX and reduce the MDA level. Conclusion The extracts of Polygala tenuifolia Wild. have antiaging action by scavenging unnecessary free radical and relieving the oxidative damage.
Keywords:Polygala ten uifolia Wild    D-galactose   Antiaging
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