| A型肉毒毒素声带注射治疗内收型痉挛性发声障碍 |
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| 引用本文： | 刘波,屈季宁,李再香,袁琨.A型肉毒毒素声带注射治疗内收型痉挛性发声障碍[J].中国误诊学杂志,2001,1(5):662-663. |
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| 作者姓名： | 刘波 屈季宁 李再香 袁琨 |
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| 作者单位： | 1. 武汉市第二医院耳鼻咽喉科
2. 湖北医科大学附属第一医院耳鼻咽喉-头颈外科, |
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| 摘 要： | 目的 探讨双侧声带注射A型肉毒毒素治疗内收性痉挛必发声障碍疗效。方法 在直接喉镜下于双侧声带近外侧甲榴肌处注射A型肉毒毒索各2.5U治疗内收性痉挛性发声障碍11例。结果 均在注射后24h即显效，发声改善平均持续时间16.2wK，不良反应有暂时过度呼吸音11例、饮水呛咳5例，吞咽困难3例，未发现A型肉毒毒素全身毒副作用。结论 直接喉镜下A型肉毒毒素双侧声带注射是治疗内收性痉挛性发声障碍有效、安全、简便的方法。
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| 关 键 词： | 痉挛性发声障碍 诊断 注射治疗 A型肉毒毒素 |
| 文章编号： | 1009-6647(2001)05-0662-02 |
| 修稿时间： | 2001年1月20日 |
Adductor Spasmodic Dysphonia Treated by Injecting of Botulinum Toxin A into Vocal Cords |
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| LIU Bo,QU Ji ning,LI Zai xiang,et al.Adductor Spasmodic Dysphonia Treated by Injecting of Botulinum Toxin A into Vocal Cords[J].Chinese Journal of Misdiagnostics,2001,1(5):662-663. |
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| Authors: | LIU Bo QU Ji ning LI Zai xiang |
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| Abstract: | Objective To investigate the effect of botulinum toxin A(BTA) injected into vocal cords for the treatment of adductor spasmodic dysphonia (SD) by direct lanyngoscopy.Methods 11 patients with adductor SD were treated by injection on both vocal cords each with 2.5U of BTA by direct laryngoscopy.Results All patient's phonation improved within the first 24 hours,with sustained improvement from 12 to 21 weeks with an average of 16.2 weeks.The local side effect included breathy voice in all cases and mild choking sensation when drinking fluids in 5 cases,dysphagia in 3 cases.No systemic adverse reactions were noted.Conclusion The injection of BTA on both vocal cords by direct laryngoscopy is an effective,safe and simple method for the treatment of adductor SD. |
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| Keywords: | spasmodic dysphonia/diagnosis spasmodic dysphonia/therapy inject |
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