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5个不同产地半夏镇咳作用的实验研究
引用本文:刘婷,秦彩玲,张毅,武桂兰,李东成,李春英.5个不同产地半夏镇咳作用的实验研究[J].中国实验方剂学杂志,2007,13(9):35-36.
作者姓名:刘婷  秦彩玲  张毅  武桂兰  李东成  李春英
作者单位:中国中医科学院中药研究所,北京,100700
摘    要:目的:比较不同产地半夏的镇咳效果。方法:采用小鼠氨水引咳法,观测5个不同产地半夏的镇咳作用,以Bliss法计算出各产地半夏咳嗽次数抑制率的ED50.结果:甘肃西和、四川绵阳、云南昭通、湖北天门、安徽南陵5个产地的半夏对氨水诱发的小鼠咳嗽均有不同程度的抑制作用,其抑制咳嗽次数的ED。分别为2.76,3.01,14.34,0.47,0.70g生药/kg。结论:不同产地的半夏均表现出一定的镇咳功效,但其ED50差别较大。

关 键 词:半夏  镇咳  半数有效量
文章编号:1005-9903(2007)09-0035-03
收稿时间:2006-07-03
修稿时间:2006-07-03

Antitussive Effect of Pinellia temata(Thunb.) Breit.Growing in Five Different Environments
LIU Ting,QIN Cai-ling,ZHANG Yi,WU Gui-lan,LI Dong-cheng,LI Chun-ying.Antitussive Effect of Pinellia temata(Thunb.) Breit.Growing in Five Different Environments[J].China Journal of Experimental Traditional Medical Formulae,2007,13(9):35-36.
Authors:LIU Ting  QIN Cai-ling  ZHANG Yi  WU Gui-lan  LI Dong-cheng  LI Chun-ying
Institution:Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beifing 100700, China
Abstract:Objective:To compare the antitussive action of pinellia temata(Thunb.)Breit.growing in different environment.Methods:By using nehulixation of NH3 aq.in mice,observe the antitussive effect of pinellia temata(Thunb.)Breit.growing in different environemnt,and calculate the ED50 of the inhibitory rate for cough times induced by NH3 aq.in mice.Results:Pinellia temata(Thunb.)Breit.in Gansu-XiHe,Sichuan-MianYang,Yunnan-Zhao Tong,Hubei-TianMen,and Anhui-NanLing demonstrated different antitussive effect,the ED50 of the inhibitory rate of cough times were 2.76,3.01,14.34,0.47,and 0.70 g·kg-1.Conclusion:Pinellia temata(Thunb.)Breit.growing in different environment demonstrated obvious antitussive action,but the ED50 of the inhibitory rate of cough times had big difference.
Keywords:Pinellia temata(Thunb  )Breit    antitussive action  ED_(50)  
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