原发性开角型青光眼患者手术前后焦虑抑郁情绪的影响因素分析

目的:分析原发性开角型青光眼(POAG)患者术前及术后1个月焦虑抑郁情况的影响因素?方法:收集POAG患者83例,分别在抗青光眼手术前采用低视力者生存质量量表(LVQOL)?汉密尔顿焦虑量表(HAMA)及汉密尔顿抑郁量表(HAMD)?家庭支持量表进行测试,术后1个月采用HAMA?HAMD和LVQOL进行测试?正常人83例作为对照组,采用HAMA?HAMD进行测试?评价POAG患者术前及术后1个月焦虑和抑郁的伴发率,并对年龄?性别?家庭支持?文化程度等影响因素进行分析?结果:83例POAG患者,术前焦虑及抑郁的伴发率分别为59.0%和30.1%,术后1个月焦虑及抑郁的伴发率分别为20.5%和15.7%?对照组焦虑及抑郁的伴发率分别为8.4%和4.8%?男性?家庭支持高者,术前HAMA评分低;男性?年龄小?术前生活质量高?家庭支持高者,术前HAMD评分低?Logistic回归分析显示,年龄?生存质量是术后1个月焦虑情绪的影响因素(P = 0.027,P = 0.009);生存质量是术后1个月抑郁情绪的影响因素(P = 0.047)?结论:POAG患者术前?术后1个月发生焦虑?抑郁为多种影响因素共同作用的结果,应引起临床医师重视,尽早给予心理干预?

Influencing factors of anxiety and depression among patients with primary open-angle glaucoma before and after surgical interventions

Objective:To investigate the prevalence and influential factors of anxiety and depression in patients with primary open-angle glaucoma (POAG) before and after surgical interventions. Methods:Totally 83 patients with POAG were investigated with Hamilton anxiety scale (HAMA),Hamilton depression scale(HAMD),family support scale and low vision quality-of-life questionnaire (LVQOL) preoperatively,and with LVQOL,HAMA and HAMD in one-month-post operative time. Totally 83 controls were assessed by using HAMA and HAMD. We investigated the prevalence and influential factors of anxiety and depression in patients with POAG before and after surgical interventions. Results:Of all the POAG patients,49(59.0%) of them were identified as anxiety and 25 (30.1%) of them were identified as depression preoperatively. A total of 17(20.5%) patients were identified as anxiety,and 13 (15.7%) patients were identified as depression in one-month-post operative time,whereas the incidence of anxiety and depression in the control group was 8.4% and 4.8%,respectively. Multiple linear regression analysis showed that preoperative HAMA scores were correlated with sex and family support whereas preoperative HAMD scores were correlated with sex,QOL,family support and age (P < 0.05). In multivariate logistic regression,the impact factors of anxiety in one-month-postoperative time were age and QOL (P = 0.027,P = 0.009);QOL was the factor affecting depression in one-month-postoperative time (P = 0.047). Conclusion:There existed high prevalence of anxiety and depression disorders with POAG patients before and after surgical interventions and more attentions should be paid on this phenomenon.