| 新型涂布法黑素细胞移植系统治疗白癜风临床观察 |
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| 引用本文： | 鲁 严,李 雪,周梅华,孙 杰,吴 迪,王大光,朱文元.新型涂布法黑素细胞移植系统治疗白癜风临床观察[J].南京医科大学学报,2013(3):360-363. |
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| 作者姓名： | 鲁 严 李 雪 周梅华 孙 杰 吴 迪 王大光 朱文元 |
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| 作者单位： | 南京医科大学第一附属医院皮肤科,江苏 南京 210029;南京医科大学第一附属医院皮肤科,江苏 南京 210029;南京医科大学第一附属医院皮肤科,江苏 南京 210029;南京医科大学第一附属医院皮肤科,江苏 南京 210029;南京医科大学第一附属医院皮肤科,江苏 南京 210029;南京医科大学第一附属医院皮肤科,江苏 南京 210029;南京医科大学第一附属医院皮肤科,江苏 南京 210029 |
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| 基金项目： | 国家自然科学基金(81171517);江苏省社会发展计划(BS2007072) |
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| 摘 要： | 目的:观察新型涂布黑素细胞移植系统治疗白癜风的临床疗效?方法:配制以人重组粒细胞集落刺激因子(recombinant human granulocyte colony-stimulating factor,rhG-CSF)为主要生长因子的培养基,混合卡波姆凝胶构成一种涂布载体系统用于黑素细胞移植治疗白癜风,按拟定标准进行疗效评估?结果:所有患者均有> 20%以上复色,其中6例复色面积超> 90%,11例复色70%~80%,15例复色30%~50%,有效率100%?84.4%的患者呈均匀复色,无明显斑驳现象?所有患者未出现不良反应?结论:新型涂布法黑素细胞移植系统治疗白癜风是一种安全?有效的方法?
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| 关 键 词： | 黑素细胞 移植 白癜风 卡波姆胶 |
| 收稿时间： | 2012/12/23 0:00:00 |
The clinical effect observation on the new system of coating in the treatment of vitiligo with melanocytes transplantation |
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| Lu Yan,Li Xue,Zhou Meihu,Sun Jie,Wu Di,Wang Daguang and Zhu Wenyuan.The clinical effect observation on the new system of coating in the treatment of vitiligo with melanocytes transplantation[J].Acta Universitatis Medicinalis Nanjing,2013(3):360-363. |
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| Authors: | Lu Yan Li Xue Zhou Meihu Sun Jie Wu Di Wang Daguang and Zhu Wenyuan |
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| Institution: | Department of Dermatology and Venereology,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Dermatology and Venereology,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Dermatology and Venereology,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Dermatology and Venereology,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Dermatology and Venereology,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Dermatology and Venereology,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Dermatology and Venereology,the First Affiliated Hospital of NJMU,Nanjing 210029,China |
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| Abstract: | Objective:To observe the clinical effect of melanocytes transplantation on vitiligo with coating method in 32 patients.Methods:The medium was prepared with recombinant human granulocyte colony-stimulating factor(rhG-CSF) as the major growth factor,mixed with carbomer gel to constitute the system of coating on the treatment of vitiligo with melanocytes transplantation.Therapeutic evaluation was assessed with certain standard. Results:All patients had repigmentation for more than 20%,in which the repigmentation of six cases was more than 90%,11 cases for 70% to 80% and 15 cases for 30% to 50%. The total effective rate was 100%. The 84.4% of the patients showed evenly repigmentation. No obvious mottling was observed. Conclusion:Melanocytes transplantation on vitiligo with coating method is safe and effective. |
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| Keywords: | melanocyte transplantation vitiligo carbomer gel |
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