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CD105在非小细胞肺癌中的表达及意义
引用本文:付伟,张瑞虹,刘爱东. CD105在非小细胞肺癌中的表达及意义[J]. 西南国防医药, 2011, 21(3): 239-241. DOI: 10.3969/j.issn.1004-0188.2011.03.003
作者姓名:付伟  张瑞虹  刘爱东
作者单位:1. 唐山,河北省唐山市工人医院胸外科,河北,063000
2. 唐山市协和医院超声科
3. 唐山职业技术学院病理教研室
基金项目:唐山市科学技术研究与发展指导计划项目
摘    要:目的探讨CD105的表达在非小细胞肺癌发生、发展及转移中的作用。方法应用流式细胞术检测100例非小细胞肺癌和50例正常肺组织标本中CD105的表达,分析其在不同临床特征中的表达差别。结果 CD105在非小细胞肺癌组织中的表达量明显高于正常肺组织(P〈0.05);有无胸膜侵犯、有无淋巴结转移的非小细胞肺癌患者肺癌组织之间CD105的表达差异有统计学意义(P〈0.05)。结论非小细胞肺癌患者有CD105高表达,并存在着CD105阳性的血管新生,检测CD105蛋白可能对判断患者的预后有一定价值。

关 键 词:非小细胞肺癌  CD105  表达  意义

Expression and significance of CD105 in non small-cell lung cancer
Fu We,Zhang Ruihong,Liu Aidong. Expression and significance of CD105 in non small-cell lung cancer[J]. Medical Journal of National Defending forces in Southwest China, 2011, 21(3): 239-241. DOI: 10.3969/j.issn.1004-0188.2011.03.003
Authors:Fu We  Zhang Ruihong  Liu Aidong
Affiliation:Fu We1,Zhang Ruihong2,Liu Aidong3 1.Chest Surgery,Worker's Hospital of Tangshan City,Tangshan,Hebei,063000,China,2.Department of Ultrasound,Xiehe Hospital of Tangshan City,3.Department of Pathology,Vocational and Technical College of Tangshan City
Abstract:Objective To explore the role of CD1054 expression in the occurrence,development and metastasis of non small-cell lung cancer(NSCLC).Methods Flow cytometry was used to detect CD1054 expression in samples from 100 cases of NSCLC and 50 cases of normal lung tissue.The differences of CD1054 expression among various clinical features were analyzed.Results CD1054 expression was significantly higher in NSCLC tissues than that in normal lung tissues(P<0.05).Moreover,the differences of CD1054 expression between NSC...
Keywords:CD105
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