| 依那普利联合卡维地洛治疗老年慢性心衰的临床观察 |
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| 引用本文： | 刘丹,谭志胜,杨宇.依那普利联合卡维地洛治疗老年慢性心衰的临床观察[J].西南国防医药,2011,21(5):493-495. |
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| 作者姓名： | 刘丹 谭志胜 杨宇 |
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| 作者单位： | 成都军区昆明总医院干部病房,昆明,650032 |
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| 摘 要： | 目的探讨依那普利联合卡维地洛在老年慢性心力衰竭患者治疗中的疗效、耐受性和安全性。方法选择老年充血性心力衰竭（CHF）患者130例,随机分为常规治疗组（对照组,28例）、依那普利与卡维地洛联合治疗组（观察组,42例）、依那普利治疗组31例和卡维地洛治疗组29例。4组治疗前和治疗6个月后,均使用超声心动图分别测定左心室舒张末期内径（LVEDD）、心输出量（CO）和左心室射血分数（LVEF）,进行疗效观察。结果治疗后4组LVEDD较治疗前显著减少（P〈0.05）,LVEF和CO较治疗前显著增高（P〈0.05）;治疗后观察组、LVEDD低于对照组（P〈0.05）,LVEF和CO较对照组显著增高（P〈0.05）。结论在常规治疗老年CHF患者的基础上,加用目标剂量的依那普利联合卡维地洛,对CHF患者安全有效,能明显改善心功能,提高左室射血分数。
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| 关 键 词： | 依那普利 卡维地洛 充血性心力衰竭 老年 |
Clinical observation of treatment of chronic congestive heart failure with enalapril and carvedilo in elderly patients |
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| Liu Dan,Tan Zhisheng,Yang Yu.Clinical observation of treatment of chronic congestive heart failure with enalapril and carvedilo in elderly patients[J].Medical Journal of National Defending forces in Southwest China,2011,21(5):493-495. |
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| Authors: | Liu Dan Tan Zhisheng Yang Yu |
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| Institution: | Liu Dan,Tan Zhisheng,Yang Yu Cadre's Ward,Kunming General Hospital of Chengdu Military Command,Kunming,Yunnan,650032,China |
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| Abstract: | Objective To investigate the therapeutic effects,tolerance and safety of enalapril and carvedilo in the treatment of congestive heart failure(CHF)in elderly patients.Methods 130 elderly patients with CHF were randomly divided into routine treatment group(control group,n=28),enalapril plus carvedilo treatment group(observation group,n=42),enalapril treatment group(n=31)and carvedilo treatment group(n=29).Left ventricular end diastolic diameter(LVEDD),cardiac output(CO)and left ventricular ejection fraction(L... |
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| Keywords: | enalapril carvedilo congestive heart failure |
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