| 冬虫夏草对2型糖尿病肾病大鼠细胞凋亡的影响 |
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| 引用本文： | 吕秀芳,郭新民,王桂云. 冬虫夏草对2型糖尿病肾病大鼠细胞凋亡的影响[J]. 牡丹江医学院学报, 2005, 26(1): 22-24 |
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| 作者姓名： | 吕秀芳 郭新民 王桂云 |
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| 作者单位： | 牡丹江医学院,157011;牡丹江医学院,157011;牡丹江医学院,157011 |
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| 摘 要： | 目的:讨2-型糖尿病(2-DM)肾病大鼠的肾脏细胞凋亡及中药冬虫夏草的影响作用.方法:随机选取以冬虫夏草大、中、小剂量灌胃的2-DM肾病大鼠,以安慰剂灌胃的2-DM肾病大鼠及正常对照组大鼠各10只,用药8周后,采用Hoechst荧光染色法测定肾脏细胞凋亡及相关生化指标. 结果:2-DM肾病大鼠肾组织细胞凋亡明显增多,冬虫夏草组大鼠肾组织细胞凋亡较2-DM肾病模型组明显减少.结论:冬虫夏草可抑制2-DM肾病大鼠肾组织细胞凋亡.
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| 关 键 词： | 细胞凋亡 2-型糖尿病肾病 冬虫夏草 |
| 修稿时间： | 2004-11-22 |
EFFECT OF CORDYCEPTS SINENSIS ON CELL APOPTOSIS IN KIDNEY OF 2-DIABETIC NEPHROPHY MICE |
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| Lu Xiufang et al Mudanjiang Medical College. EFFECT OF CORDYCEPTS SINENSIS ON CELL APOPTOSIS IN KIDNEY OF 2-DIABETIC NEPHROPHY MICE[J]. Journal of Mudanjiang Medical College, 2005, 26(1): 22-24 |
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| Authors: | Lu Xiufang et al Mudanjiang Medical College |
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| Affiliation: | Lu Xiufang et al Mudanjiang Medical College 157011 |
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| Abstract: | Objective:To investigate the Cell apoptosis and the effect of Cordyceps sinensis on cell apoptosis in kidney of 2-Diabetic nephrophy mice. Methods :making two random groups of ten 2-Diabetic nephrophy mice we administered by gavage Cordyceps sinensis to one of them and placebo for to another 8 weeks as a control group Then the apoptosis was evaluated by Hoechst fluorescence straining method and other relative biochemistry target by biochemistry method. Results: The Apoptotic cells in kidney of 2-Diabetic nephrophy mice were more than the normal mice. After Cordyceps sinensis given, Obvious decrease was found in number of apoptotic cells compared with the 2-Diabetic nephrophy model group.Conclusion:Cordyceps sinensis may inhibit the cell apoptosis in kidney of 2-Diabetic nephrophy mice. |
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| Keywords: | Cell apoptosis 2-Diabetic nephropathy Cordyceps sinensis |
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