脑梗死与血脂、血糖、血尿酸水平的关系探讨

目的: 探讨脑梗死患者血脂、血糖、血尿酸水平变化及其临床意义。方法: 检测60例脑梗死患者的7项血脂指标以及血糖(GLU)、血尿酸(UA),并与对照组30例的检测结果进行比较。结果: 脑梗死患者的胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、载脂蛋白B (ApoB)、脂蛋白(a)Lp (a)]、GLU含量均高于对照组(P<0.05~P<0.001),载脂蛋白A1(ApoA1)含量显著低于对照组(P<0.001),UA和高密度脂蛋白(HDL)含量变化差异均无统计学意义(P>0.05)。结论: TC、TG、LDL、ApoB、Lp (a)、GLU的水平升高,ApoA1下降与脑梗死均有一定关系,应重视对高血脂、高血糖的积极防治。

Relationship between cerebral infarction and levels of blood lipids,blood glucose and uric acid

Objective:To explore the relationship between cerebral infarction(CI)and the levels of blood lipids,blood glucose and serum uric acid.Methods:Seven indices of serum lipids and blood glucose(GLU),serum uric acid(UA)in 60 patients with CI(patient group)and 30 cases without CI(control group)were measured and compared.Results:The serum levels of total cholesterol(TC),triglyceride(TG),low-density lipoprotein(LDL),apolipoprotein B(ApoB),lipoprotein(a)Lp(a),GLU were obviously higher in the cerebral infarction group than those in the control group(P<0.05-P<0.001),but apolipoprotein A1(Apo A1)was significantly lower(P<0.001).There was no significant difference in high-density lipoprotein(HDL)and UA levels between cerebral infarction group and control group(P>0.05).Conclusions:The results suggest that the higher levels of TC,TG,LDL,ApoB,Lp(a),GLU and lower levels of ApoA1 are related to CI to a certain extent,which indicates that it is necessary to actively control and prevent the hyperlipidemia and the high blood glucose.