Surgical strategies for chronic pancreatitis in a 1,327- patient Scandinavian Baltic pancreatic Club (SBPC) register |
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| Affiliation: | 1. Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland;2. Faculty of Medicine and Health Technology, Tampere University, Finland;3. Department of Surgery, Oslo University Hospital, Oslo, Norway;4. Department of Surgery, Lithuanian University of Health Sciences, Kaunas, Lithuania;5. Centre for Pancreatic Diseases, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Denmark;6. Department of Gastroenterology, Haukeland University Hospital, Norway;7. Department of Clinical Medicine, University of Bergen, Norway;8. Division of Gastroenterology, Digestive Disease Center K, Bispebjerg Hospital, Copenhagen, Denmark;9. Herlev Copenhagen University Hospital/Herlev, University of Copenhagen, Copenhagen, Denmark;10. Pancreatitis Centre East (PACE), Copenhagen University Hospital Hvidovre, Copenhagen, Denmark;1. Department of Gastroenterology and Human Nutrition Unit, All India Institute of Medical Sciences, New Delhi, India;2. Department of Pathology, All India Institute of Medical Sciences, New Delhi, India;3. Centre of Biomedical Research, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India;4. Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India;1. Department of Surgery, Kansai Medical University, 2-5-1 Shin-machi, Hirakata City, Osaka, 573-1010, Japan;2. Cancer Treatment Center, Kansai Medical University, 2-5-1 Shin-machi, Hirakata City, Osaka, 573-1010, Japan;3. Department of Thoracic Oncology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata City, Osaka, 573-1010, Japan;4. Third Department of Internal Medicine, Kansai Medical University, 2-5-1 Shin-machi, Hirakata City, Osaka, 573-1010, Japan;5. Department of Pathology, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan;6. Division of Surgical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA;1. Department of Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryomachi, Aobaku, Sendai, 980-8574, Japan;2. Department of Gastroenterological, General, Breast and Thyroid Surgery, Yamagata University Graduate School of Medical Science, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan;1. Department of Radiology, Peking Union Medical College Hospital, Beijing, China;2. Department of General Surgery, Peking Union Medical College Hospital, Beijing, China;3. Department of Pathology, Peking Union Medical College Hospital, Beijing, China;1. Department of Upper Digestive Diseases, Karolinska University Hospital and Department of Clinical Science, Intervention, and Technology, Karolinska Institute, Stockholm, Sweden;2. Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden;3. Department of Surgical and Perioperative Sciences, Surgery, Umeå University, Sweden |
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| Abstract: | BackgroundChronic pancreatitis (CP) may cause intermittent or continuous pain and complications requiring invasive interventions. No specific recommendations for surgical interventions have been presented. Our aim was to determine the surgical treatment strategies for the treatment of CP in the Scandinavian and Baltic countries.MethodsThis multi-centre cross sectional study included 1327 CP patients from eight centres. The data was gathered from the Scandinavian Baltic Pancreatic Club (SBPC) database. Patients who underwent pancreatic surgery were analysed. The baseline CP population from the eight centres was used as a reference. The information registered included comorbidities, pancreatic function, previous interventions, time and type of surgery and the EORTC-30 quality of life (QOL) questionnaire.ResultsOverall, 95/1327 (7%) patients underwent pancreatic surgery. Fifty-one (54%) of these underwent pancreatic surgery for chronic pain (PSCP) and formed the final study group. Median follow-up time was two (range 0–8) years after surgery and seven (1–46) years after diagnosis. The most common surgical procedures were pancreatic resection combined with drainage (54%) followed by pancreatic resections (32%) and drainage procedures (14%). Postoperatively, 47% of the patients were pain free with or without pain medication while 16% had chronic pain episodes, this did not differ from the base CP population. In QOL questionnaires, PSCP patients reported the same QOL but worse social functioning and more symptoms compared to the CP population.ConclusionsPancreatic surgery for CP is rare: surgical procedures were performed on only 7% of the CP patients in the SBPC database. In half of the patients the indication was pain. Most of these patients underwent endoscopic procedures before surgery. Half of the patients reported being pain-free after surgery. |
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