Acquired chronic candidiasis treated with transfer factor |
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Authors: | C. C. BENZ J. W. THOMAS M. MANDL NORMA MORGAN |
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Affiliation: | Departments of Medicine and Pathology, University of British Columbia, The Vancouver General Hospital and St Paul's Hospital, Vancouver, British Columbia, Canada |
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Abstract: | A patient with acquired chronic oral and vaginal candidiasis resistant to topical and parenteral therapy was found to have impaired cell mediated immunity to Candida antigen and loss of skin test response to tuberculin (Mantoux). Treatment with Candida-active transfer factor produced clinical remission lasting 1 year and restitution of in vitro and in vivo immune parameters. Relapse occurred while receiving a second lot of transfer factor from the same donor. Subsequent treatment with levamisole was associated with onset of agranulocytosis. |
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