家族性巨颌症的诊断与治疗--附7例报告及文献复习

目的 探讨家族性巨颌症，临床特点及治疗。方法 对7例患的临床资料进行回顾性分析。结果 临床表现为广泛性、无痛性和对称性的上下颌骨膨隆，下颌骨(7／7)多于上颌骨(4／7)。3例有家族史。X线表现为多房囊性阴影。4例术前得到正确诊断。5例采用保守的手术治疗。结论 家族性巨颌症应与巨细胞肉芽肿及骨巨细胞瘤相鉴别。由于该病青春期后有自愈性，较轻的患无需手术，较严重的患保守的手术治疗效果理想。

Diagnosis and treatment of cherubism

Objective To study the clinical features and treatment of cherubism Methods The clinical data of 7 cases were analyzed retrospectively. Results The patients presented with progressive, painless, symmetrical expansion of the maxilla and mandible. 3 cases had the positive family history. The lesions showed the appearances of bilateral multilocular radiolucent area on radiography. 4 cases had been confirmed diagnosis before operations. 5 cases underwent the conservative operations. Conclusion cherubism should be differentiatied with giant cell granulomas and giant cell tumor of bone. The majority patients with cherubism can recover by themselves after puberty. The therapy effect of conservative operation in serious cases is satisfied.