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Zinc deficiency manifested by dermatitis and visual dysfunction in a patient with Crohn's disease
Authors:Seung Jae Myung  Suk-Kyun Yang  Hwoon-Yong Jung  Sung-Ae Jung  Gyeong Hoon Kang  Hyun Kwon Ha  Weon-Seon Hong  Young Ii Min
Affiliation:(1) Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea, KR;(2) Department of Diagnostic Pathology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea, KR;(3) Department of Diagnostic Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea, KR
Abstract:We report a case of Crohn's disease with low serum zinc concentration in a 26-year-old woman. She demonstrated acrodermatitis enteropathica and decreased visual acuity during total parenteral nutrition. Subsequent intravenous zinc supplementation resulted in alleviation of the skin lesions and improvement of visual acuity. This case supports the notion that depressed serum zinc in Crohn's disease may cause clinical manifestations, such as acrodermatitis enteropathica and retinal dysfunction, which may be correctable with zinc supplementation. (Received Nov. 12, 1997; accepted May 22, 1998)
Keywords:: zinc  Crohn's disease  acrodermatitis enteropathica  visual dysfunction
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