In vitro activities of MK-826 (L-749,345) against 363 strains of anaerobic bacteria |
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Authors: | Wexler H M Molitoris D Finegold S M |
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Institution: | Research Services, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA. hwexler@ucla.edu |
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Abstract: | The activity of MK-826 was compared to the activities of cefoxitin, ceftriaxone, imipenem, and meropenem against 363 gram-negative and gram-positive anaerobes by using NCCLS procedures. At least 98% of the strains were susceptible to the carbapenems. All strains of Clostridium perfringens, Fusobacterium nucleatum, Peptostreptococcus, and Sutterella wadsworthensis were susceptible to all agents tested. |
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