创伤性骨折并发脂肪栓塞综合征的临床观察

目的通过14例脂肪栓塞综合征（FES）患者发生的情况，探讨其早期的诊断及治疗。方法分析2001年5月至2005年7月发生脂肪栓塞综合征14例。将其分为A组和B组：A组在治疗早期即给予大剂量甲基强的松龙（200mg）；B组给予小剂量甲基强的松龙（100mg）。结果经过早期诊断和及时的处理，13例患者全部治愈，1例死亡；两组在血气分析和血氧浓度分析中各指标均有所提高，PaO2、SpO2、Hb及血小板数目均有提高，心率明显下降，与治疗前有显著性差异（P〈0．05，P〈0．01）；两组间无统计学差异。结论对于创伤性骨折，要警惕脂肪栓塞综合征的发生，应及时处理，并在治疗早期大剂量使用大剂量甲基强的松龙，加快痊愈。

Clinical study of fat embolism syndrome traumatic fracture

Objective To investigate the treatment effect of fat embolism syndrome. Methods To review 14 patients were fat embolism syndrome （FES）. Divided them into group A and B, group A were treated with 200 mg,while group B were 100 mg in the early teatment,the other treatments were the same with each other. Results Through the early diagnosis and treatment,13 FES patients were cured but 1 was dead. The value of PaO2, SpO2,Hb and platelet counts increased and the HR recuded after treatment in both group on blood gas and blood oxygen saturation, which have significant diffrence compred with these values before treatment （P 〈 0. 05, P 〈 0. 01 ） ; there were no difference between two groups. Conclusion Traumatic fracture should be payed atterntion to FES,which must be treated and used big dose of methylprednisolone to faster recovery.