Optimal phases of dynamic CT for detecting hepatocellular carcinoma: evaluation of unenhanced and triple-phase images |
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| Authors: | T Kim T Murakami S Takahashi K Tsuda K Tomoda Y Narumi H Oi M Sakon H Nakamura |
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| Institution: | (1) Department of Radiology, Osaka University Medical School, 2-2 Yamadaoka, Suita City, Osaka 565-0871, Japan, JP;(2) Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita City, Osaka 565-0871, Japan, JP |
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| Abstract: | Background: To determine the optimal phases of dynamic computed tomography (CT) for detecting hepatocellular carcinoma (HCC).
Methods: Fifty-two patients with 85 HCC nodules were examined by means of unenhanced and triple-phase CT images of the whole liver.
The time for obtaining the arterial-phase images was 25–55 s after intravenous bolus injection of contrast material, the time
for obtaining the portal venous-phase images was 65–100 s, and the time for obtaining late-phase images was 145 s to 4 min.
Detectability of the HCC nodules for all phases was statistically compared.
Results: The detection rates for the arterial- and late-phase images were significantly higher than for the unenhanced and portal
venous-phase images (p < 0.01). The combination of arterial- and late-phase images showed the same number of HCC nodules in the same number of patients
as did the combination of unenhanced and triple-phase images.
Conclusion: The combination of the arterial- and late-phase imagings was best for detecting HCC nodules.
Received: 8 July 1998/Revision accepted: 18 November 1998 |
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| Keywords: | : Liver neoplasms— Computed tomography (CT)— Contrast media— Helical |
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