| 高强度聚焦超声治疗恶性骨肿瘤的实验研究 |
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| 引用本文： | 陈文直,伍烽,朱辉,白晋,王智彪.高强度聚焦超声治疗恶性骨肿瘤的实验研究[J].中华超声影像学杂志,2001,10(5):313-315. |
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| 作者姓名： | 陈文直 伍烽 朱辉 白晋 王智彪 |
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| 作者单位： | 重庆医科大学附属第二医院肿瘤中心 |
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| 基金项目： | 国家"九五"科技重点攻关项目(96-02-01)和国家自然科学基金委员会项目资助(39770841) |
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| 摘 要： | 目的 探讨高强度聚焦超声（HIFU）治疗恶性骨肿瘤的可行性。方法 12只VX2移植性骨肿瘤兔接受HIFU治疗，采用超声检查、组织病理学方法观察HIFU治疗后移植性骨肿瘤的变化。结果 HIFU治疗后骨内、外肿瘤组织的回声增强，肿瘤组织凝固性坏死。结论 HIFU治疗兔移植性VX2骨肿瘤是可行的。
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| 关 键 词： | 高强度聚焦超声 骨肿瘤 治疗 实验性肿瘤 |
| 修稿时间： | 2000年8月9日 |
High intensity focused ultrasound in the treatment of experimental malignant bone tumor |
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| CHEN Wenzhi,WU Feng,ZHU Hui,et al..High intensity focused ultrasound in the treatment of experimental malignant bone tumor[J].Chinese Journal of Ultrasonography,2001,10(5):313-315. |
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| Authors: | CHEN Wenzhi WU Feng ZHU Hui |
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| Institution: | CHEN Wenzhi,WU Feng,ZHU Hui,et al. Clinical Center for Tumor Therapy,the second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China |
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| Abstract: | Objective To investigate the feasibility of high intensity focused ultrasound (HIFU) in the treatment of malignant bone tumors.Methods Twelve rabbits with VX 2 carcinoma implanted in bone received HIFU sonication and were assessed changes of targeted bone tumors using B mode ultrasonic and pathological histology after treatment.Results After HIFU therapy, the echograms of targeted bone tumors were enhanced, pathological finds showed that targeted tumor cells appeared coagulative death.Conclusions HIFU can effectively and safely treat rabbit VX 2 carcinoma implanted in bone. |
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| Keywords: | High intensity focused ultrasound Bone neoplasms/therapy Neoplasms experimental |
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