老年高血压左室肥厚与血压变异性的关系

目的 :探讨老年高血压左室肥厚 (LVH)与血压变异性 (L BPV)的关系。方法 :对 10 6例伴有或不伴有LVH的老年原发性高血压 (EH)患者进行 2 4小时动态血压监测 ,并与年龄相近的正常血压者 4 0例进行对比 ,分析血压的变异性。结果 :与正常对照组比较 ,LVH与无LVH组患者的 2 4小时收缩压标准差 (2 4hSSD) ,2 4小时舒张压标准差 (2 4hDSD) ;昼间收缩压标准差(dSSD) ,舒张压标准差 (dDSD) ;夜间收缩压标准差 (nSSD) ,舒张压标准差 (nDSD)均显著增大 (P <0 0 5 )。LVH组较无LVH组的 2 4hSSD、2 4hDSD、dSSD显著增大 (P <0 0 5 )。结论 :EH患者心血管交感、迷走神经功能失衡 ,伴LVH时这种改变更明显。EH患者的BPV变化 ,与LVH呈正相关

The relationship between left ventricular hypertrophy and blood pressure variability in elderly patients with essential hypertension

Objective:To study the relationship between left ventricular hypertrophy(LVH) and blood pressure variability(BPV) in elderly patients with essential hypertension(EH).Methods:24 hours ambulatory blood pressure monitors were carried in 106 elderly EH patients with or without LVH and in 40 patients as normal controls.The blood pressure variability in three groups was analyzed.Results:Not only the standard deviation of 24 hours systolic pressure(24hSSD),24 hours diastolic pressure(24hDSD),day time systolic pressure(dSSD),diastolic pressure(dDSD),night time systolic pressure(nSSD),and diastolic pressure(nDSD) were much higher in study group than that in controls group, respectively (P<0 05);but also the 24hSSD,24hDSD and dSSD in LVH group were higher than those in without LVH group(P<0 05).Conclusions:There were cardiovascular sympathetic and vagal nerve system dysfunctions in EH patients,and the disorder in LVH group was obvious.The BPV in EH patients had positively relevant with LVH.