| 冬凌草甲素的提取工艺研究 |
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| 引用本文： | 王宁,谢国祥,史晓浩,倪力军,赵军,凌峰.冬凌草甲素的提取工艺研究[J].医学教育探索,2003(10):901-902. |
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| 作者姓名： | 王宁 谢国祥 史晓浩 倪力军 赵军 凌峰 |
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| 作者单位： | [1]上海雷允上药业有限公司，上海200001 [2]华东理工大学化学与制药学院，上海200237 |
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| 基金项目： | “十五”国家科技攻关计划项目 (2 0 0 1BA70 1A0 4) |
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| 摘 要： | 目的 采用近红外光谱(NIR)技术对冬凌草中冬凌草甲素的提取工艺进行研究。方法 采用柱色谱法分离冬凌草甲素，应用NIR技术寻找最佳工艺条件。结果 此工艺所得冬凌草甲素纯度较高，且样品与对照品的HPLC峰保留时间相同，NMR和IR图谱相同。结论 本法洗脱速度快，安全、成本低、方便，并且重现性好。
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| 关 键 词： | 冬凌草 冬凌草甲素 柱色谱法 近红外光谱 |
Study on method for extracting and separating oridonin in Rabdosia rubescens |
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| WANG Ning,XIE Guo xiang,SHI Xiao hao,NI Li jun,ZHAO Jun,LING Feng.Study on method for extracting and separating oridonin in Rabdosia rubescens[J].Researches in Medical Education,2003(10):901-902. |
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| Authors: | WANG Ning XIE Guo xiang SHI Xiao hao NI Li jun ZHAO Jun LING Feng |
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| Abstract: | Object To study the most suitable conditions of the extraction separation process of the oridonin in Rabdosia rubescens (Hemsl.) Hara with NIR. Methods The oridonin was chromatographed on a silica column and found the optimum conditions with NIR. Results The oridonin extracted by this method had higher purity. The retention time of the sample was the same as that of the reference substance. The spectra of NMR and IR are the same. Conclusion This method is proved to be fast, safe, lower cost, simple and has good reproducibility. |
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| Keywords: | Rabdosia rubescens (Hemsl ) Hara oridonin column chromatography NIR |
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