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| 仙人掌提取物对小鼠镇痛作用的实验研究 | |
| 引用本文： | 韦国锋,韦启后,黄祖良,李振中,何有成,石登燕,陈丽.仙人掌提取物对小鼠镇痛作用的实验研究[J].右江民族医学院学报,2003,25(5):597-599. |
| 作者姓名： | 韦国锋 韦启后 黄祖良 李振中 何有成 石登燕 陈丽 |
| 作者单位： | 1. 右江民族医学院应用化学研究室,广西百色533000 2. 右江民族医学院免疫学教研室,广西百色533000 3. 右江民族医学院2000级医学检验本科,广西百色533000 |
| 基金项目： | 广西自然科学基金资助课题 (桂科基 0 2 3 60 74) |
| 摘 要： | 目的 观察仙人掌提取物对小鼠的镇痛作用。方法 采用扭体法和温浴法分别对小鼠腹腔注射仙人掌提取物(仙人掌组 )、阿斯匹林 (阿司匹林组 )及等容量生理盐水 (生理盐水组 ) 1ml,仙人掌组又分别予 0 .5ml、1ml不同剂量给药 ,比较各组扭体数和痛阈潜伏期的变化。结果 以仙人掌提取物对扭体法致痛的小鼠镇痛作用明显优于阿斯匹林及生理盐水 ,χ2 分别为 4.8,15 .0 ,P <0 .0 5或 0 .0 0 1,温浴法给药后不同时间痛阈潜伏期也明显长于阿斯匹林组和生理盐水组 ,P <0 .0 5或 0 .0 1。结论 仙人掌提取物对小鼠具有显著的镇痛作用 |
| 关 键 词： | 仙人掌 提取物 镇痛 小鼠 |
| 文章编号： | 1001-5817(2003)05-0597-03 |
| 修稿时间： | 2003年6月28日 |
Experimental Study of Abirritation of CACTI Extracts on Mice |
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| WEI Guo-feng ,WEI Qi-hou ,HUANG Zhu-liang ,LI Zhen-zhong ,HE You-cheng ,SHI Deng-yan,CHEN Li.Experimental Study of Abirritation of CACTI Extracts on Mice[J].Journal of Youjiang Medical College For Nationalities,2003,25(5):597-599. | |
| Authors: | WEI Guo-feng WEI Qi-hou HUANG Zhu-liang LI Zhen-zhong HE You-cheng SHI Deng-yan CHEN Li |
| Institution: | WEI Guo-feng 1,WEI Qi-hou 2,HUANG Zhu-liang 1,LI Zhen-zhong 1,HE You-cheng 1,SHI Deng-yan3,CHEN Li 3 |
| Abstract: | Objective To study the abirritation of CACTI extracts on Mice. Methods mouse writhing method and warm bathing method: 1ml intraperitoneal administrations of CACTI extracts (CACTI Group), aspirin (Aspirin Group) and normal saline (Normal Saline Group) were given respectively, of which, dosages of 0.5ml and 1ml were administered to the CACTI Group to compare and study changes of mouse writhing numbers and delitescence of threshold of pain. Results In the mouse writhing method, the abirritation of the CACTI Group distinctly out matched the other two groups, with χ 2 to be4.8, 15.0, P<0.05 or 0.001. in the warm bathing administration, durations of delitescence of threshold of pain also significantly prolonged in the CACTI Group than the other two groups with P<0.05 or 0.01. Conclusion CACTI extracts have a significant abirritation on mice. |
| Keywords: | CACTI extracts abirritation mouse |
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