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Guanabenz as inhibitor of copper-containing amine oxidases |
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| Authors: | G Banchelli B Bertocci L Raimondi G Soldani M Del Tacca F Buffoni |
| Abstract: | The effects of guanabenz on some copper containing amine oxidases are described. Guanabenz 'in vitro' inhibits pig plasma benzylamine oxidase with a IC50 M 5.1 +/- 0.8 X 10(-6) M. It also inhibits pig kidney diamine oxidase and rat liver mitochondrial monoamine oxidase at higher concentrations. The significance of this property of guanabenz is discussed. |
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