| 应用蚕豆根尖微核试验技术对二氧化氯消毒剂诱变性的研究 |
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| 引用本文： | 蒋辉权,倪晓平,寇宇. 应用蚕豆根尖微核试验技术对二氧化氯消毒剂诱变性的研究[J]. 癌变．畸变．突变, 2001, 13(2): 98-101. DOI: 10.3969/j.issn.1004-616x.2001.02.010 |
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| 作者姓名： | 蒋辉权 倪晓平 寇宇 |
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| 作者单位： | 杭州市疾病预防控制中心, 浙江 杭州 310006 |
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| 摘 要： | 目的与方法:采用蚕豆根尖微核试验技术对两种市售二氧化氯(ClO2) 的诱变性进行研究。结果:在ClO2 的稀释度为1 :100时,杭州产ClO2 (A 样) 与余杭产ClO2 (B 样) 蚕豆根尖细胞微核率(MNF) 分别为(17. 91 ±4. 80) ‰和(17. 57 ±3. 15) ‰。,与作为阴性对照的自来水相比较,均有显著的统计学差异( P < 0. 01) ,并呈现较强的剂量2反应关系。结论:消毒剂ClO2 能诱发蚕豆根尖细胞微核率的增加,具有一定的诱变性。
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| 关 键 词： | 蚕豆 微核试验 二氧化氯 诱变性 |
| 文章编号： | 1004-616X(2001)02-0098-04 |
| 收稿时间： | 2000-08-28 |
| 修稿时间： | 2000-11-16 |
THE MUTAGENICITY STUDY OF CHLORINE DIOXIDE USING MICRONUCLEUS TEST IN VICIA FABA ROOT TIP CELLS |
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| JNG Hui-quan,NI Xiao-ping,KOU Yu. THE MUTAGENICITY STUDY OF CHLORINE DIOXIDE USING MICRONUCLEUS TEST IN VICIA FABA ROOT TIP CELLS[J]. Carcinogenesis,Teratogenesis and Mutagenesis, 2001, 13(2): 98-101. DOI: 10.3969/j.issn.1004-616x.2001.02.010 |
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| Authors: | JNG Hui-quan NI Xiao-ping KOU Yu |
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| Affiliation: | Center of Disease Prevention and Control in Hangzhou, Hangzhou 310006, China |
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| Abstract: | Purpose and Methods : The mutagenecity of two batches of chlorine dioxide (ClO2) were studide using-micronucleus test in V icia f aba root tip cells. Results : The f requencies of micronucleus of two kinds of ClO2 were (17. 91 ±4. 80) ‰ and (17. 5 ±3. 12) ‰ respectively when the diluent multiple of ClO2 was at 1 : 100.=Comparing with the tap water group , the differences (χ2A= 30. 57 , χ2B-= 29. 60 P < 0. 01) was statisticallysignificant and the dose2effect relationship ws clear. Conclusion : Clorine dioxide has mutagenicity. We should pay attention to safety of it s apllication in food and water. |
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| Keywords: | Vicia faba micronucleus test chlorine dioxide mutagenicity |
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