Variation in virulence among oculogenital serovars of Chlamydia trachomatis in experimental genital tract infection. |
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| Authors: | J I Ito Jr J M Lyons L P Airo-Brown |
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| Affiliation: | Department of Infectious Diseases, City of Hope National Medical Center, Duarte, California 91010. |
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| Abstract: | Seven different oculogenital serovars (D, E, F, G, H, I, and K) of Chlamydia trachomatis were inoculated intravaginally into CF-1 mice, and subsequent infection was monitored. The duration of infection was longest with serovars D and E. This may help to explain clinical surveys which demonstrate a high (50%) prevalence of these serovars. Furthermore, a comparison of the invasiveness of strains D and H demonstrated a much higher frequency of uterine horn infection with serovar D. |
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