| 电生理测试作为早期青光眼诊断指标的横断面研究 |
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| 作者姓名： | Laila Hassan M Elshazly Amal A. ElGohary Iman A. Fahmy |
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| 作者单位： | 1. 12511,埃及开罗吉萨纪念眼科学研究所眼科;2. 12511,埃及开罗吉萨眼科研究所;3. 12511,埃及开罗吉萨眼科研究所眼科 |
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| 摘 要： | 明视负向反应(PhNR)和图形视网膜电图(PERG)的结果作为评估青光眼的诊断指标.10例对照组和15例早期青光眼患者接受了完整的眼科检查,包括视力测量,眼压(IOP)测量,眼底检查和视野检查.同时进行图形视网膜电图和全视野视网膜点图纪录.青光眼组的平均偏差和图形平均标准偏差显著较低(P＜0.001,P＜0.01).PERGN95,PhNR,b波以及PhNR/b波的幅值显著较低(P＜0.001).眼压升高降低了PERG与PhNR的振幅.
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| 关 键 词： | 青光眼 电生理 明视负向反应 |
| 收稿时间： | 2016/5/30 0:00:00 |
| 修稿时间： | 2016/10/17 0:00:00 |
Elecrophysiological tests as an early glaucoma indicator: a cross sectional study |
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| Laila Hassan M Elshazly,Amal A. ElGohary,Iman A. Fahmy.Elecrophysiological tests as an early glaucoma indicator: a cross sectional study[J].International Journal of Ophthalmology,2017,17(1):26-29. |
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| Authors: | Laila Hassan M Elshazly Amal A ElGohary and Iman A Fahmy |
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| Institution: | Department of Ophthalmology, Memorial Institute of Ophthalmology, Giza, Cairo 12511, Egypt,Department of Vision Science, Research Institute of Ophthalmology, Giza, Cairo 12511, Egypt and Department of Ophthalmology, Research Institute of Ophthalmology, Giza, Cairo 12511, Egypt |
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| Abstract: | The role of photopic negative response(PhNR)and pattern electroretinogram(PERG)was assessed as diagnostic indicator of glaucoma. Ten control subjects and 15 patients with early glaucoma underwent complete ophthalmological examination including visual acuity measurement, intraocular pressure(IOP)measurement, fundus examination and visual field examination. Pattern ERG and photopic full-field ERG were performed. Mean deviation(MD)and pattern standard deviation(PSD)means were significantly reduced in glaucoma group(P<0.001 and P<0.01). The amplitudes of PERG N95, PhNR, b-wave and the PhNR/b-wave ratio were significantly reduced(P<0.001). The rise in IOP resulted in reduction of PERG and PhNR amplitude. |
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| Keywords: | glaucoma electrophysiology photopic negative response |
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