Sustained remission of CIDP associated with Evans syndrome |
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Authors: | Knecht Hans Baumberger Michael Tobòn Aurelio Steck Andreas |
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Institution: | Institute for Clinical Research, Swiss Paraplegic Centre, CH-6207 Nottwil (Lucerne), Switzerland. hans.knecht@paranet.ch |
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Abstract: | A patient with chronic inflammatory demyelinating polyneuropathy (CIDP) developed Evans syndrome (hemolytic anemia/thrombocytopenia) 17 months after onset of symptoms despite different immunomodulatory treatments. A therapeutic approach with the chimeric monoclonal anti-CD20 antibody rituximab induced substantial improvement of CIDP and hematologic recovery. The patient remains in sustained remission 17 months after completion of therapy. Rituximab may represent a successful therapy in otherwise refractory CIDP. |
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