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误诊为脊柱关节病的成人散发性低磷性骨软化症1例报告
引用本文:高洁,蔡青. 误诊为脊柱关节病的成人散发性低磷性骨软化症1例报告[J]. 第二军医大学学报, 2013, 34(2): 227-229
作者姓名:高洁  蔡青
作者单位:第二军医大学长海医院风湿免疫科,上海,200433
基金项目:上海市科委基础研究重点项目(08JC1406300)
摘    要:脊柱关节病(spondyloarthropathy)即血清类风湿因子阴性脊柱关节病,是一组相互关联的多系统的炎性关节疾病[1],包括强直性脊柱炎、反应性关节炎、银屑病关节炎、炎性肠病性关节炎及未定型脊柱关节病等.慢性炎性腰背痛是脊柱关节病的主要临床特点.低磷性骨软化症是一种由于低磷血症造成的骨基质不能以正常方式进行矿化的代谢性骨病[2],该病临床少见,疾病初期易因腰背痛、非甾类抗炎药治疗有效等类似炎性腰背痛的临床表现而误诊为脊柱关节病.本文总结1例曾误诊为脊柱关节病的成人低磷性骨软化症患者的临床资料,并结合文献复习低磷性骨软化症与脊柱关节病的诊断及鉴别诊断方法,旨在提高临床的诊断水平.

关 键 词:低磷血症  骨软化症  脊柱关节病  诊断  鉴别诊断  误诊
收稿时间:2012-06-05
修稿时间:2012-07-17

Adult-onset sporadic hypophosphatemic osteomalacia misdiagnosed as spondyloarthropathy: a case report
GAO Jie and CAI Qing. Adult-onset sporadic hypophosphatemic osteomalacia misdiagnosed as spondyloarthropathy: a case report[J]. Former Academic Journal of Second Military Medical University, 2013, 34(2): 227-229
Authors:GAO Jie and CAI Qing
Affiliation:Department of Rheumatology and Immunology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China*Corresponding author.
Abstract:The disease of hypophosphatemic osteomalacia is clinically rare and easy to be misdiagnosed. It refers to a metabolic bone disease in which bone matrix can not be mineralized in the normal way due to hypophosphatemia. One case report of adult-onset sporadic hypophosphatemic osteomalacia ever misdiagnosed as spondyloarthropathy and related literature were studied. We should master the diagnosis and differential diagnosis of hypophosphatemic osteomalacia to improve the clinic diagnosis and treatment level.
Keywords:hypophosphatemia   osteomalacia   spondyloarthropathy   diagnosis   differential diagnosis   misdiagnosis
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