面神经麻痹临床数据回归分析

目的：通过多元回归分析研究本病可能的影响因素：性别、年龄、从发病到开始治疗间隔时间、病因、发病季节、证型、受累神经节段、常规治疗和发病3个月末终点评分及后遗症之间的关系。方法：根据＂周围性面神经麻痹的临床评估及疗效判定标准方案＂绘制面神经麻痹病例观察表,据该表建立数据库,用SPSS 12.0统计软件,连续型数值变量采用线性回归,二项分布数据采用逐步回归的方法,找到在P〈0.05显著水平上的Logistic简约模型,根据回归模型寻找预后的关键因素。结果：所有模型拟合良好,线性模型排除多元共线性,逐步回归模型其预报准确度都≥81.3%,回归方程如下：（1）线性回归：Y=92.468-0.149从发病到开始治疗间隔时间-1.379证型-4.291后遗症;（2）逐步回归：Logit（p85）=2.823针刺（7天内介入）-37.261;Logit（p90）=2.326春天发病＋1.401营养神经药物-46.599;Logi（tp95）=3.248春天发病＋0.143初诊评分-2.441风热阻络-2.627鼓索至镫骨肌支-30.052;Logi（tp后遗症）=2.883挑治＋2.021镫骨肌支至膝状神经节＋1.433其他病因-2.468。结论：（1）发病7天内介入针刺可使本病得到良好的恢复,针刺介入越早越好;（2）配合应用营养神经药物者预后更佳;（3）春天发病是预后良好的有利因素;（4）本病能否彻底恢复取决于初诊评分、辨证分型及受累神经节段的定位;（5）后遗症的产生与受累神经节段在镫骨肌支和病因不明密切相关。

Logistic Regression of Facial Nerve Paralysis Based on Clinical Data

Objective：The trial is trying to find the relationship among prognostic factors of idiopathic facial nerve paralysis.The prognostic factors inlude：gender,age,duration before the first visit,pathogen,season when the disease starts,syndrome,affected nerve location,regular treatment,terminal scores by 3 monthes,sequelae.Method：Make case observation tables and fill them up according to the requirement of the trial.Process the data using SPSS 12.0 software.Linear regression is applied for those continual data,while binary regression is applied for those binary data.Simple model is found after each procession,which is limited to the sig0.05 level.Based on the models,the relationship is explained.Result：All the models are well fit.Linear model excludes the collinearity.The prediction correct is no less than 81.3 percent for all the stepwise models.Linear model：Y=92.468-0.149 duration before the first visit-1.379syndrome-4.291sequelae.None linearly model：Logit（p85）=2.823acupuncture applied with 7 days-37.261;Logit（p90）=2.326spring＋1.401nerve tropic drug-46.599;Logit（p95）=3.248spring＋0.143scores of the first visit-2.441wind heat syndrome-2.627chonda tympani-30.052;Logit（psequelae）=2.883cutting therapy＋2.021stapedial branch＋1.433unclear pathogen-2.468.Conclusion：Acupuncture applied within 7 days can aid in recovery.Those whose facial paralysis start in spring and who receive nerve tropic drug will have better recovery.There is no significant relationship between complete recovery and treatment.Scores of the first visit,syndrome and affected nerve location play greater role in the recovery.There is tight relationship among sequelae,affected nerve location in stapedial branch and unclear pathogen.