脑卒中并发上消化道出血的机制及治疗进展

消化道出血是脑卒中最严重的并发症之一,发病机制不清。急性脑出血并发上消化道出血(UGH)的发生率明显高于急性脑梗死组,病变累及脑干时尤为突出。伴意识障碍的患者并发UGH的发生率较高。脑卒中并发UGH发生时间多在发病后24h内出现,亦可发生于病程10d左右。并发UGH的脑卒中患者病死率明显高于未并发UGH者。脑卒中并发UGH预后不良,早期应采取措施,积极预防。

Cerebral Stroke and Upper Gastrointestinal Hemorrhage

Gastrointestinal hemorrhage is one of the most heavily complications of cerebral stroke. The pathological mechanism is unclear. The incidence rate of upper gastrointestinal hemorrhage（UGH） is higher in the eases of acute cerebral hemorrhage than that of acute cerebral infarction, especially in the cases of brain stem stroke. The incidence rate of UGH is higher in patients with conscious disturbance. The eases of acute cerebral stroke complicated by UGH always occur within 24 hours, while some cases happened in 10 days. The incidents rate of death is especially higher in patients of acute cerebral stroke complicated by UGH than in patients non-complicated by UGH. The patients of acute cerebral stroke complicated by UGH have a poor prognosis,preventive measures should be made at early stage.