Reduced Peak Atrial Systolic Mitral Annular Velocity Predicts the Development of Nonvalvular Atrial Fibrillation |
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Authors: | Jin-Oh Choi M.D. Hyejin Han M.D. Soo Jin Cho M.D. Ji Hyun Yang M.D. Bong Gun Song M.D. Sang Yeub Lee M.D. Jung Hyuk Kim M.D. Sang-Chol Lee M.D. Young Keun On M.D. Jun Soo Kim M.D. Seung Woo Park M.D. |
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Affiliation: | Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea |
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Abstract: | We investigated whether the echocardiographic parameters of the left atrium (LA) can predict the development of nonvalvular atrial fibrillation (AF). Among 14,062 patients ( > 20 years old) who underwent an echocardiographic examination were evaluated, 2,606 patients who underwent follow-up ECG with an interval of > 6 months were investigated. Newly developed AF was noted in 42 (1.6%) patients with follow-up duration of 31.8 ± 8.9 months. Cox regression analysis revealed that a higher left atrial volume index (hazard ratio [HR ]= 1.06; 95% confidence interval [CI] 1.03–1.09, P < 0.001), relative wall thickness (RWT) of ≥ 0.407 (HR = 2.74, 95% CI 1.39–5.41, P = 0.004), a reduced peak atrial systolic mitral annular velocity (HR = 0.845, 95% CI 0.72–0.99, P = 0.037), and an advanced age (HR = 1.04, 95% CI 1.01–1.07, P = 0.009) were independently related to the development of nonvalvular AF. Therefore, reduced A ' , which is parameter of LA contractile function, might be an important predictor for the development of nonvalvular AF. |
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Keywords: | atrial fibrillation echocardiography left atrial volume atrial function |
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