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Urolithiasis risk factors in continent reservoir ileostomy patients
Authors:Hartley Stern  Zane Cohen  Douglas R. Wilson  Donald A G. Mickle
Affiliation:1. Divisions of General Surgery, Nephrology, and Biochemistry, Toronto General Hospital, 101 College Street, Suite CW 1-102, M5G 1L7, Toronto, Ontario, Canada
Abstract:Conventional ileostomy patients are at an increased risk to urinary stone formation compared to normal controls. This study was designed to evaluate any further risk factors to urinary stone formation in patients with Kock ileostomies. Nine Kock ileostomy patients were matched for age, sex, and body weight with nine conventional ileostomy patients and nine controls. Two 24-hour urine samples from each patient were analyzed for volume, pH, Na+/K+ ratio, oxalate, and uric acid concentration. Both ileostomy groups demonstrated reduced urinary volume and Na+/K+ ratio as compared to the control groups (P<0.05). The Kock ileostomy group had the lowest urinary volume. There was no significant reduction in urinary pH or elevation in urine uric acid concentration in the Kock ileostomy group. The results suggest that there is no significantly added risk to uric acid stone formation in Kock ileostomy patients
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