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Nonablative Dermal Remodeling With a 585-nm, 350-μsec, Flashlamp Pulsed Dye Laser: Clinical and Ultrastructural Analysis
Authors:David Goldberg  MD    M. Tan  MD    M. Dale Sarradet  MD     Marsha Gordon MD
Affiliation:Skin Laser and Surgery Specialists of New York and New Jersey, Hackensack, New Jersey,;Mount Sinai School of Medicine, New York, NY
Abstract:BACKGROUND.   A nonablative 350-μsec, 585-nm, flashlamp pulsed dye laser is currently being used for the treatment of rhytides.
OBJECTIVE.   To analyze both clinical rhytid improvement and electron microscopic evidence of ultrastructural changes after treatment with a nonablative 350-μsec, 585-nm, flashlamp pulsed dye laser.
RESULTS.   At 6 months after two treatments, 40% of the treated subjects noted mild improvement in rhytid appearance. Nontreating physician evaluation revealed some degree of improvement in 50% of the treated subjects. Mild improvement in quality and texture of the skin was also reported by 50% of the subjects. Electron microscopic evaluation showed ultrastructural changes that are consistent with new collagen formation.
CONCLUSION.   Treatment with a nonablative 350-μsec, 585-nm, flashlamp pulsed dye laser can lead to both clinical and electron microscopic evidence of improvement in photo-damaged skin.
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