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内囊出血大鼠血浆及心肌孤啡肽水平变化研究
引用本文:黄兴城,罗晓阳,陈学华,吴润华,张素芬,陈艳玲. 内囊出血大鼠血浆及心肌孤啡肽水平变化研究[J]. 中华神经外科疾病研究杂志, 2005, 4(6): 529-531
作者姓名:黄兴城  罗晓阳  陈学华  吴润华  张素芬  陈艳玲
作者单位:东莞市太平人民医院神经外科,广东,东莞,523900
摘    要:目的研究内囊出血大鼠血浆及心肌组织匀浆中孤啡肽含量变化及在急性心肌损害中的作用.方法通过建立大鼠内囊出血模型,用放免法(RIA)测定血浆及心肌组织匀浆中孤啡肽含量.结果大鼠内囊出血组血浆及心肌组织匀浆中孤啡肽含量明显高于对照组(P<0.01).结论孤啡肽含量变化在内囊出血后急性心肌损害过程中起重要作用.

关 键 词:内囊出血  血浆  孤啡肽  心肌组织
文章编号:1671-2897(2005)04-529-03
收稿时间:2005-03-22
修稿时间:2005-06-12

Research on levels of orphanin FQ in the plasma and the myocardial tissue of rat after internal capsule hemorrhage
HUANG Xingcheng,LUO Xiaoyang,CHEN Xuehua,WU Runhua,ZHANG Sufen,CHEN Yanling. Research on levels of orphanin FQ in the plasma and the myocardial tissue of rat after internal capsule hemorrhage[J]. Chinese Journal of Neurosurgical Disease Research, 2005, 4(6): 529-531
Authors:HUANG Xingcheng  LUO Xiaoyang  CHEN Xuehua  WU Runhua  ZHANG Sufen  CHEN Yanling
Abstract:Objective To observe the level changes of orphanin FQ in the plasma and the myocardial tissue of rat with internal capsule hemorrhage.Methods The levels of orphanin FQ in the plasma and the myocardial tissue of rat with internal capsule hemorrhage were determined by radioimmunoassay (RIA).Results Levels of orphanin FQ in the plasma and the myocardial tissue of rat with internal capsule hemorrhage increased significantly (P<0.01). Conclusion Orphanin FQ plays an important role in causing myocardial injury after internal capsule hemorrhage.
Keywords:Internal capsule hemorrhage   Plasma   Myocardial tissue   Orphanin FQ
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