Low-frequency (<1 Hz) oscillations in the human sleep electroencephalogram |
| |
| Affiliation: | 1. Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, 72076 Tübingen, Germany;2. German Center for Diabetes Research (DZD), 72076 Tübingen, Germany;3. Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, 72076 Tübingen, Germany;4. School of Psychology, University of Birmingham, B15 2TT Birmingham, UK;5. Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, University Hospital of Tübingen, 72076 Tübingen, Germany;1. Dept. of Psychiatry, Univ. of North Carolina, Chapel Hill, NC 27514-5307, United States;2. Dept. Cell Biology and Physiology, Univ. of North Carolina, Chapel Hill, NC 27514-5307, United States;3. Dept. of Biomedical Engineering, Univ. of North Carolina, Chapel Hill, NC 27514-5307, United States;4. Neuroscience Center, Univ. of North Carolina, Chapel Hill, NC 27514-5307, United States;5. Dept. of Neurology, Univ. of North Carolina, Chapel Hill, NC 27514-5307, United States;6. Carolina Center for Neurostimulation, Univ. of North Carolina, Chapel Hill, NC 27514-5307, United States;7. Experimental Psychology Lab, Dept. of Psychology, Cluster for Excellence “Hearing for All”, European Medical School, Carl von Ossietzky Univ., Oldenburg, Germany;8. Res. Ctr. Neurosensory Sci., Carl von Ossietzky Univ., Oldenburg, Germany;1. Université Paris Descartes, Sorbonne Paris Cité, Équipe d''accueil VIgilance FAtigue SOMmeil (VIFASOM) EA 7330, France;2. Université Paris Descartes, Sorbonne Paris Cité, APHP, HUPC, Hôtel Dieu, Centre du Sommeil et de la Vigilance, Paris, France;3. Institut de Recherche Biomédicale des Armées (IRBA), Brétigny-sur-Orge, France;4. Rythm SAS, Paris, France;5. Team Memory, Oscillations and Brain states (MOBs), Brain Plasticity Unit, CNRS, ESPCI Paris, PSL Research University, Paris, France;1. Center for Advanced Research in Sleep Medicine, Centre de Recherche de l’Hôpital du Sacré-Cœur de Montréal, Montréal, QC, Canada;2. Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, United States;3. Département de Psychiatrie, Université de Montréal, Montréal, QC, Canada;1. School of Psychology, University of Birmingham, Birmingham B15 2TT, United Kingdom;2. Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen 72076, Germany;3. Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany;4. Centre for Integrative Neuroscience, University of Tübingen, Tübingen 72076, Germany;1. Institut d’Investigaciones Biomèdiques Augus Pi i Sunyer (IDIBAPS), Roselló 149–153, 08036 Barcelona, Spain;2. ICREA, Passeig Lluís Companys 23 08010 Barcelona, Spain |
| |
| Abstract: | Low-frequency (<1 Hz) oscillations in intracellular recordings from cortical neurons were first reported in the anaesthetized cat and then also during natural sleep. The slow sequences of hyperpolarization and depolarization were reflected by slow oscillations in the electroencephalogram. The aim of the present study was to examine whether comparable low-frequency components are present in the human sleep electroencephalogram. All-night sleep recordings from eight healthy young men were subjected to spectral analysis in which the low-frequency attenuation of the amplifier was compensated. During sleep stages with a predominance of slow waves and in the first two episodes of non-rapid-eye-movement sleep, the mean power spectrum showed a peak at 0.7–0.8 Hz (range 0.55–0.95 Hz). The typical decline in delta activity from the first to the second non-rapid-eye-movement sleep episode was not present at frequencies below 2 Hz. To detect very low frequency components in the pattern of slow waves and sleep spindles, a new time series was computed from the mean voltage of successive 0.5 s epochs of the low-pass (<4.5 Hz) or band-pass (12–15 Hz) filtered electroencephalogram. Spectral analysis revealed a periodicity of 20–30 s in the prevalence of slow waves and a periodicity of 4 s in the occurrence of activity in the spindle frequency range.The results demonstrate that distinct components below 1 Hz are also present in the human sleep electroencephalogram spectrum. The differences in the dynamics between the component with a mean peak value at 0.7–0.8 Hz and delta waves above 2 Hz is in accordance with results from animal experiments. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
