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体检人群脂肪肝与代谢综合征及其组份的相关性分析
引用本文:曾洪利,王宏宝,刘 颖,张春玉.体检人群脂肪肝与代谢综合征及其组份的相关性分析[J].大连医科大学学报,2011,33(4):366-369.
作者姓名:曾洪利  王宏宝  刘 颖  张春玉
作者单位:1. 大连医科大学附属第二医院内分泌科,辽宁大连116027;大连医科大学,辽宁大连116044
2. 大连医科大学附属第二医院体检中心,辽宁大连,116027
3. 大连医科大学附属第二医院内分泌科,辽宁大连,116027
摘    要:目的]了解体检人群脂肪肝的患病情况并分析其与血脂之间的相关性.方法]收集体检中心8009例健康受检者的临床资料,计算各年龄组脂肪肝的患病率;并按有无脂肪肝分为脂肪肝组和非脂肪肝组,比较两组甘油三酯(TG)、胆固醇(CHOL)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL - C)均值差异有无统计学意...

关 键 词:脂肪肝  代谢综合征  血脂  患病率  相关性

Relationship between Fatty Liver and Metabolic Syndrome
ZENG Hong-li,WANG Hong-bao,LIU Ying and ZHANG Chun-yu.Relationship between Fatty Liver and Metabolic Syndrome[J].Journal of Dalian Medical University,2011,33(4):366-369.
Authors:ZENG Hong-li  WANG Hong-bao  LIU Ying and ZHANG Chun-yu
Institution:1(1.Department of Endocrinology,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China;2.Grade 2004,Seven-year Program of Dalian Medical University,Dalian 116044,China;3.Department of Health Examination Center,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China)
Abstract:Objective] To explore the prevalence of the fatty liver,and to analyze its relationship with metabolic syndrome.Methods] This cross-sectional study randomly included 8009 people.We computed the prevalence of fatty liver of different age groups.According to the availability of fatty liver,they were divided into fatty liver and non-fatty liver groups,the difference of two groups were compared in triglyceride(TG),cholesterol(CHOL),high-density lipoprotein cholesterol(HDL-C) and low-density lipoprotein cholesterol(LDL-C).The relationship between fatty liver and its components of metabolic syndrome was analyzed.Results](1) The prevalence of the fatty liver was 26.0%,35.9% in males and 13.2% in females and in comparison the difference was significant statistically(P<0.001).In less than 50 years old age group,the average level of CHOL and LDL-C in fatty liver group was higher than that in non-fatty liver group(P<0.001),and in over 70 years old age group,the average level of CHOL in fatty liver group was higher than that in non-fatty liver group(P<0.001).(2) In every age group,mean TG in fatty liver group was higher than that in non-fatty liver group.HDL-C in fatty liver group was lower than that in non-fatty liver group(P<0.001).(3) The fatty liver was positively correlated with triglyceride,cholesterol,low-density lipoprotein cholesterol BMI,hyperglycemia and hypertension(P<0.001),and negatively correlated with HDL-C(P<0.001).Conclusions](1) The prevalence of fatty liver in males is higher than that in females.(2) The fatty liver is associated with metabolic syndrome and its components.TG,CHOL,LDL-C,BMI,hyperglycemia and hypertension are risk factors of fatty liver,while HDL-C is a protective factor of fatty liver.
Keywords:fatty liver  metabolic syndrome  serum lipid-profile  prevalence  relevance
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